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10.1016/j.cub.2014.08.057 http://scihub22266oqcxt.onion/10.1016/j.cub.2014.08.057 C4252622!4252622!25308076     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Biol 2014 ; 24 (20): 2411-6 Nephropedia Template TP {{tp|p=25308076|t=2014. Anaerobic Bacteria Grow within Candida albicans Biofilms and Induce Biofilm Formation in Suspension Cultures |pdf=|usr=}}{{25308076}} gab.com Text Anaerobic Bacteria Grow within Candida albicans Biofilms and Induce Biofilm Formation in Suspension Cultures JO: Curr Biol http://www.kidney.de/pget.php?&tw=1&pmid=25308076 #FOAvip The human microbiome contains diverse microorganisms, which share and compete for the same environmental niches [1, 2]. A major microbial growth form in the human body is the biofilm state, where tightly packed bacterial, archaeal and fungal cells must cooperate and/or compete for resources in order to survive [3?6]. We examined mixed biofilms composed of the major fungal species of the gut microbiome, C. albicans, and each of five prevalent bacterial gastrointestinal inhabitants: Bacteroides fragilis, Clostridium perfringens, Escherichia coli, Klebsiella pneumoniae and Enterococcus faecalis [7?10]. We observed that biofilms formed by C. albicans provide a hypoxic microenvironment that supports the growth of two anaerobic bacteria, even when cultured in ambient oxic conditions that are normally toxic to the bacteria. We also found that co-culture with bacteria in biofilms induces massive gene expression changes in C. albicans, including upregulation of WOR1, which encodes a transcription regulator that controls a phenotypic switch in C. albicans, from the ?white? cell type to the ?opaque? cell type. Finally, we observed that in suspension cultures, C. perfringens induces aggregation of C. albicans into ?mini-biofilms,? which allow C. perfringens cells to survive in a normally toxic environment. This work indicates that bacteria and C. albicans interactions modulate the local chemistry of their environment in multiple ways to create niches favorable to their growth and survival. Twit Text FOAVip Anaerobic Bacteria Grow within Candida albicans Biofilms and Induce Biofilm Formation in Suspension Cultures ????Curr Biol http://www.kidney.de/pget.php?&tw=1&pmid=25308076 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25308076 #FOAvip English Wikipedia <ref>{{Cite pmid|25308076}}</ref> Anaerobic Bacteria Grow within Candida albicans Biofilms and Induce Biofilm Formation in Suspension Cultures #MMPMID25308076 Fox EP; Cowley ES; Nobile CJ; Hartooni N; Newman DK; Johnson AD Curr Biol 2014[Oct]; 24 (20): 2411-6 PMID25308076show ga The human microbiome contains diverse microorganisms, which share and compete for the same environmental niches [1, 2]. A major microbial growth form in the human body is the biofilm state, where tightly packed bacterial, archaeal and fungal cells must cooperate and/or compete for resources in order to survive [3?6]. We examined mixed biofilms composed of the major fungal species of the gut microbiome, C. albicans, and each of five prevalent bacterial gastrointestinal inhabitants: Bacteroides fragilis, Clostridium perfringens, Escherichia coli, Klebsiella pneumoniae and Enterococcus faecalis [7?10]. We observed that biofilms formed by C. albicans provide a hypoxic microenvironment that supports the growth of two anaerobic bacteria, even when cultured in ambient oxic conditions that are normally toxic to the bacteria. We also found that co-culture with bacteria in biofilms induces massive gene expression changes in C. albicans, including upregulation of WOR1, which encodes a transcription regulator that controls a phenotypic switch in C. albicans, from the ?white? cell type to the ?opaque? cell type. Finally, we observed that in suspension cultures, C. perfringens induces aggregation of C. albicans into ?mini-biofilms,? which allow C. perfringens cells to survive in a normally toxic environment. This work indicates that bacteria and C. albicans interactions modulate the local chemistry of their environment in multiple ways to create niches favorable to their growth and survival. äAnaerobic Bacteria Grow within Candida albicans Biofilms and Induce Bi(epmc).pdf DeepDyve Pubget Overpricing