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2014 ; 10
(4
): 360-3
Nephropedia Template TP
gab.com Text
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Using drug-intoxicated deaths as potential organ donors: impression of attendees
at the American college of medical toxicology 2014 annual scientific meeting
#MMPMID25023224
Wood DM
; Chan WL
; Dargan PI
J Med Toxicol
2014[Dec]; 10
(4
): 360-3
PMID25023224
show ga
INTRODUCTION: Over the last decade, there has been a reduction of organ donation
from intracranial haemorrhage-, stroke- and blunt trauma-related deaths in the
USA. There has been a corresponding increase in the use of drug-intoxicated
patients as organ donors from 2.1 % in 2003 to 6.8 % in 2013. METHODS:
Questionnaire survey of attendees at the American College of Medical Toxicology
2014 Annual Scientific Meeting breakout session on transplantation from deaths
related to poisoning was performed. Participants were asked whether they would
recommend the use of solid organs from cocaine- or carbon monoxide-related death
before and after the breakout session. RESULTS: Forty-eight US participants
(attending 23, fellow 15, resident 3 and other (including non-medical) 7)
completed the survey, and 97.8 and 89.1 % of participants would consider cocaine-
and carbon monoxide-related deaths for potential organ donation pre-breakout
session, respectively; this increased to 100 % for both post-breakout sessions.
There was variability in the consideration of different solid organs (the heart,
lungs, liver, pancreas and kidneys)-76.2-95.2 and 76.2-85.7 % for individual
solid organs for cocaine- and carbon monoxide-related deaths, respectively. For
both scenarios, participants were least likely to consider potential heart
donation (76.2 % of participants for both), which increased to 100 % following
the breakout session. CONCLUSIONS: Medical toxicologists have some reservation in
recommending solid organs for transplantation from deaths from cocaine and carbon
monoxide. Given the decrease in potential organ donors from typical methods of
death, further work is needed to promote organ donation in deaths related to
acute poisoning.