Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1128/IAI.01838-14 http://scihub22266oqcxt.onion/10.1128/IAI.01838-14 C4249291!4249291!25183735     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Infect+Immun 2014 ; 82 (12): 4921-30 Nephropedia Template TP {{tp|p=25183735|t=2014. Bacterial Lysis Liberates the Neutrophil Migration Suppressor YbcL from the Periplasm of Uropathogenic Escherichia coli |pdf=|usr=}}{{25183735}} gab.com Text Bacterial Lysis Liberates the Neutrophil Migration Suppressor YbcL from the Periplasm of Uropathogenic Escherichia coli JO: Infect Immun http://www.kidney.de/pget.php?&tw=1&pmid=25183735 #FOAvip Uropathogenic Escherichia coli (UPEC) modulates aspects of the innate immune response during urinary tract infection to facilitate bacterial invasion of the bladder epithelium, a requirement for the propagation of infection. For example, UPEC-encoded YbcL suppresses the traversal of bladder epithelia by neutrophils in both an in vitro model and an in vivo murine cystitis model. The suppressive activity of YbcL requires liberation from the bacterial periplasm, though the mechanism of release is undefined. Here we present findings on the site of action of YbcL and demonstrate a novel mode of secretion for a UPEC exoprotein. Suppression of neutrophil migration by purified YbcLUTI, encoded by cystitis isolate UTI89, required the presence of a uroepithelial layer; YbcLUTI did not inhibit neutrophil chemotaxis directly. YbcLUTI was released to a greater extent during UPEC infection of uroepithelial cells than during that of neutrophils. Release of YbcLUTI was maximal when UPEC and bladder epithelial cells were in close proximity. Established modes of secretion, including outer membrane vesicles, the type II secretion system, and the type IV pilus, were dispensable for YbcLUTI release from UPEC. Instead, YbcLUTI was liberated during bacterial death, which was augmented upon exposure to bladder epithelial cells, as confirmed by detection of bacterial cytoplasmic proteins and DNA in the supernatant and enumeration of bacteria with compromised membranes. As YbcLUTI acts on the uroepithelium to attenuate neutrophil migration, this mode of release may represent a type of altruistic cooperation within a UPEC population during colonization of the urinary tract. Twit Text FOAVip Bacterial Lysis Liberates the Neutrophil Migration Suppressor YbcL from the Periplasm of Uropathogenic Escherichia coli ????Infect Immun http://www.kidney.de/pget.php?&tw=1&pmid=25183735 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25183735 #FOAvip English Wikipedia <ref>{{Cite pmid|25183735}}</ref> Bacterial Lysis Liberates the Neutrophil Migration Suppressor YbcL from the Periplasm of Uropathogenic Escherichia coli #MMPMID25183735 Lau ME; Danka ES; Tiemann KM; Hunstad DA Infect Immun 2014[Dec]; 82 (12): 4921-30 PMID25183735show ga Uropathogenic Escherichia coli (UPEC) modulates aspects of the innate immune response during urinary tract infection to facilitate bacterial invasion of the bladder epithelium, a requirement for the propagation of infection. For example, UPEC-encoded YbcL suppresses the traversal of bladder epithelia by neutrophils in both an in vitro model and an in vivo murine cystitis model. The suppressive activity of YbcL requires liberation from the bacterial periplasm, though the mechanism of release is undefined. Here we present findings on the site of action of YbcL and demonstrate a novel mode of secretion for a UPEC exoprotein. Suppression of neutrophil migration by purified YbcLUTI, encoded by cystitis isolate UTI89, required the presence of a uroepithelial layer; YbcLUTI did not inhibit neutrophil chemotaxis directly. YbcLUTI was released to a greater extent during UPEC infection of uroepithelial cells than during that of neutrophils. Release of YbcLUTI was maximal when UPEC and bladder epithelial cells were in close proximity. Established modes of secretion, including outer membrane vesicles, the type II secretion system, and the type IV pilus, were dispensable for YbcLUTI release from UPEC. Instead, YbcLUTI was liberated during bacterial death, which was augmented upon exposure to bladder epithelial cells, as confirmed by detection of bacterial cytoplasmic proteins and DNA in the supernatant and enumeration of bacteria with compromised membranes. As YbcLUTI acts on the uroepithelium to attenuate neutrophil migration, this mode of release may represent a type of altruistic cooperation within a UPEC population during colonization of the urinary tract. äBacterial Lysis Liberates the Neutrophil Migration Suppressor YbcL fro(epmc).pdf DeepDyve Pubget Overpricing