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10.1259/bjr.20140451

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suck abstract from ncbi


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pmid25271412      Br+J+Radiol 2014 ; 87 (1044): ä
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  • Mesenteric panniculitis: prevalence, clinicoradiological presentation and 5-year follow-up #MMPMID25271412
  • van Putte-Katier N; van Bommel EFH; Elgersma OE; Hendriksz TR
  • Br J Radiol 2014[Dec]; 87 (1044): ä PMID25271412show ga
  • Objective:: To determine prevalence, clinicoradiological characteristics and outcome of patients with mesenteric panniculitis (MP) in a large hospital-based population. Methods:: Consecutive abdominal CT examinations of 3820 patients were evaluated for MP. Clinical characteristics, therapy and outcome of patients with MP were evaluated during a 5-year follow-up period. A matched pair analysis was performed to further investigate the relation between MP and malignancy. Results:: 94 (2.5%) patients with MP were identified (mean age, 66.6?±?11.2 years, 70.2% male). MP coexisted with malignancy (especially prostatic carcinoma) in 48.9% of patients, and this was slightly but significantly higher than in age- and sex-matched control patients (n?=?188, 46.3%). In 48 patients, MP was presumed to be idiopathic. The most frequent presenting symptom was pain (54.3%). Laboratory findings revealed increased acute-phase reactants in half of the patients with MP. CT findings included increased density of mesenterial fat (mean, ?56.8?±?10.8?HU), fat ring sign, tumoural pseudocapsule and small soft-tissue nodules. Patients with MP (14.6%) developed significantly more malignancies during a 5-year follow-up than did the control group (6.9%). One patient was treated with prednisone without satisfactory response. Conclusion:: The prevalence of MP in this study was 2.5%. In most patients, radiologic features included increased mesenteric fat density, fat ring sign and small soft-tissue nodules. MP was associated with a significant higher prevalence of coexisting malignancies and a higher prevalence of future cancer development. Advances in knowledge:: A more accurate prevalence of MP on CT is demonstrated. An underlying malignancy may play a role.
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