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2014 ; 16
(12
): 880-4
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Treatment of transient neonatal diabetes mellitus: insulin pump or insulin
glargine? Our experience
#MMPMID25437016
Passanisi S
; Timpanaro T
; Lo Presti D
; Mammė C
; Caruso-Nicoletti M
Diabetes Technol Ther
2014[Dec]; 16
(12
): 880-4
PMID25437016
show ga
Neonatal diabetes mellitus (NDM) results from impaired insulin secretion,
occurring within the first 6 months of life. NDM is classified as transient NDM
(TNDM) or permanent NDM. To date there are no universal guidelines regarding its
management. Intravenous insulin infusion represents the first and most adequate
therapeutic approach for sustained hyperglycemia, but this can provide only a
short-term solution. Several factors should be taken into account in the choice
of the long-term treatment. We describe our experience with two infants affected
by TNDM. The first child was treated with continuous subcutaneous insulin
infusion, whereas the second infant was treated with subcutaneous insulin
glargine injections. Our experience shows that the two different therapeutic
approaches, if properly managed, are equally effective.
|*Precision Medicine
[MESH]
|Diabetes Mellitus/blood/*drug therapy
[MESH]
|Female
[MESH]
|Humans
[MESH]
|Hyperglycemia/*prevention & control
[MESH]
|Hypoglycemia/chemically induced/*prevention & control
[MESH]
|Hypoglycemic Agents/administration & dosage/adverse effects/*therapeutic use
[MESH]
|Infant, Newborn
[MESH]
|Injections, Subcutaneous
[MESH]
|Insulin Glargine
[MESH]
|Insulin Infusion Systems
[MESH]
|Insulin, Long-Acting/administration & dosage/adverse effects/therapeutic use
[MESH]
|Insulin/administration & dosage/adverse effects/*therapeutic use
[MESH]