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2014 ; 281
(1797
): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Late-born intermittently fasted juvenile garden dormice use torpor to grow and
fatten prior to hibernation: consequences for ageing processes
#MMPMID25377448
Giroud S
; Zahn S
; Criscuolo F
; Chery I
; Blanc S
; Turbill C
; Ruf T
Proc Biol Sci
2014[Dec]; 281
(1797
): ä PMID25377448
show ga
Torpor is thought to slow age-related processes and to sustain growth and
fattening of young individuals. Energy allocation into these processes represents
a challenge for juveniles, especially for those born late in the season. We
tested the hypothesis that late-born juvenile garden dormice (Eliomys quercinus)
fed ad libitum ('AL', n = 9) or intermittently fasted ('IF', n = 9) use short
torpor bouts to enhance growth and fat accumulation to survive winter. IF
juveniles displayed more frequent and longer torpor bouts, compared with AL
individuals before hibernation. Torpor frequency correlated negatively with
energy expenditure and water turnover. Hence, IF juveniles gained mass at the
same rate, reached similar pre-hibernation fattening and displayed identical
hibernating patterns and mass losses as AL animals. We found no group differences
in relative telomere length (RTL), an indicator of ageing, during the period of
highest summer mass gain, despite greater torpor use by IF juveniles. Percentage
change in RTL was negatively associated with mean and total euthermic durations
among all individuals during hibernation. We conclude that torpor use promotes
fattening in late-born juvenile dormice prior to hibernation. Furthermore, we
provided the first evidence for a functional link between time spent in euthermy
and ageing processes over winter.