Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.cytogfr.2014.05.002 http://scihub22266oqcxt.onion/10.1016/j.cytogfr.2014.05.002 C4234691!4234691 !24909568     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24909568 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24909568 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cytokine+Growth+Factor+Rev 2014 ; 25 (5 ): 543-50 Nephropedia Template TP {{tp|p=24909568 |t=2014. IFIT1: A dual sensor and effector molecule that detects non-2 -O methylated viral RNA and inhibits its translation |pdf=|usr=}}{{24909568 }} gab.com Text IFIT1: A dual sensor and effector molecule that detects non-2 -O methylated viral RNA and inhibits its translation JO: Cytokine Growth Factor Rev http://www.kidney.de/pget.php?&tw=1&pmid=24909568 #FOAvip Our understanding of the antiviral actions of IFIT1, one of the most strongly induced interferon stimulated genes (ISGs), has advanced remarkably within the last few years. This review focuses on the recent cellular, biochemical, and structural discoveries that have provided new insight as to how IFIT1 functions as both a sensor and effector molecule of the cellular innate immune system. IFIT1 can detect viral RNA lacking 2'-O methylation on their cap structures or displaying a 5'-triphosphate moiety and inhibit their translation or sequester them from active replication. Because of these inhibitory actions, many viruses have evolved unique mechanisms to evade IFIT1 to facilitate replication, spread of infection, and disease pathogenesis. Twit Text FOAVip IFIT1: A dual sensor and effector molecule that detects non-2 -O methylated viral RNA and inhibits its translation ????Cytokine Growth Factor Rev http://www.kidney.de/pget.php?&tw=1&pmid=24909568 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24909568 #FOAvip English Wikipedia <ref>{{Cite pmid|24909568 }}</ref> IFIT1: A dual sensor and effector molecule that detects non-2 -O methylated viral RNA and inhibits its translation #MMPMID24909568 Diamond MS Cytokine Growth Factor Rev 2014[Oct]; 25 (5 ): 543-50 PMID24909568 show ga Our understanding of the antiviral actions of IFIT1, one of the most strongly induced interferon stimulated genes (ISGs), has advanced remarkably within the last few years. This review focuses on the recent cellular, biochemical, and structural discoveries that have provided new insight as to how IFIT1 functions as both a sensor and effector molecule of the cellular innate immune system. IFIT1 can detect viral RNA lacking 2'-O methylation on their cap structures or displaying a 5'-triphosphate moiety and inhibit their translation or sequester them from active replication. Because of these inhibitory actions, many viruses have evolved unique mechanisms to evade IFIT1 to facilitate replication, spread of infection, and disease pathogenesis. |Adaptor Proteins, Signal Transducing [MESH] |Animals [MESH] |Carrier Proteins/genetics/immunology/*metabolism/*pharmacology [MESH] |Humans [MESH] |Methylation [MESH] |Nucleic Acid Conformation [MESH] |Protein Biosynthesis [MESH] |RNA, Viral/*metabolism [MESH] |RNA-Binding Proteins [MESH]IFIT1: A dual sensor and effector molecule that detects non-2 -O methy(epmc).pdf DeepDyve Pubget Overpricing