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10.1111/psyp.12345 http://scihub22266oqcxt.onion/10.1111/psyp.12345 C4234198!4234198!25387705     free     free     free Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 259.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 259.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Psychophysiology 2014 ; 51 (12): 1246-58 Nephropedia Template TP {{tp|p=25387705|t=2014. Heritability and molecular-genetic basis of the P3 event-related brain potential: A genome-wide association study |pdf=|usr=}}{{25387705}} gab.com Text Heritability and molecular-genetic basis of the P3 event-related brain potential: A genome-wide association study JO: Psychophysiology http://www.kidney.de/pget.php?&tw=1&pmid=25387705 #FOAvip P3 amplitude is a candidate endophenotype for disinhibitory psychopathology, psychosis, and other disorders. The present study is a comprehensive analysis of the behavioral- and molecular-genetic basis of P3 amplitude and a P3 genetic factor score in a large community sample (N = 4,211) of adolescent twins and their parents, genotyped for 527,829 single nucleotide polymorphisms (SNPs). Biometric models indicated that as much as 65% of the variance in each measure was due to additive genes. All SNPs in aggregate accounted for approximately 40% to 50% of the heritable variance. However, analyses of individual SNPs did not yield any significant associations. Analyses of individual genes did not confirm previous associations between P3 amplitude and candidate genes but did yield a novel association with myelin expression factor 2 (MYEF2). Main effects of individual variants may be too small to be detected by GWAS without larger samples. Twit Text FOAVip Heritability and molecular-genetic basis of the P3 event-related brain potential: A genome-wide association study ????Psychophysiology http://www.kidney.de/pget.php?&tw=1&pmid=25387705 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25387705 #FOAvip English Wikipedia <ref>{{Cite pmid|25387705}}</ref> Heritability and molecular-genetic basis of the P3 event-related brain potential: A genome-wide association study #MMPMID25387705 MALONE SM; VAIDYANATHAN U; BASU S; MILLER MB; MCGUE M; IACONO WG Psychophysiology 2014[Dec]; 51 (12): 1246-58 PMID25387705show ga P3 amplitude is a candidate endophenotype for disinhibitory psychopathology, psychosis, and other disorders. The present study is a comprehensive analysis of the behavioral- and molecular-genetic basis of P3 amplitude and a P3 genetic factor score in a large community sample (N = 4,211) of adolescent twins and their parents, genotyped for 527,829 single nucleotide polymorphisms (SNPs). Biometric models indicated that as much as 65% of the variance in each measure was due to additive genes. All SNPs in aggregate accounted for approximately 40% to 50% of the heritable variance. However, analyses of individual SNPs did not yield any significant associations. Analyses of individual genes did not confirm previous associations between P3 amplitude and candidate genes but did yield a novel association with myelin expression factor 2 (MYEF2). Main effects of individual variants may be too small to be detected by GWAS without larger samples. äHeritability and molecular-genetic basis of the P3 event-related brain(epmc).pdf DeepDyve Pubget Overpricing