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10.1111/psyp.12348 http://scihub22266oqcxt.onion/10.1111/psyp.12348 C4231542!4231542!25387708     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Psychophysiology 2014 ; 51 (12): 1285-99 Nephropedia Template TP {{tp|p=25387708|t=2014. Heritability and molecular genetic basis of acoustic startle eye blink and affectively modulated startle response: A genome-wide association study |pdf=|usr=}}{{25387708}} gab.com Text Heritability and molecular genetic basis of acoustic startle eye blink and affectively modulated startle response: A genome-wide association study JO: Psychophysiology http://www.kidney.de/pget.php?&tw=1&pmid=25387708 #FOAvip Acoustic startle responses have been studied extensively in relation to individual differences and psychopathology. We examined three indices of the blink response in a picture-viewing paradigm?overall startle magnitude across all picture types, and aversive and pleasant modulation scores?in 3,323 twins and parents. Biometric models and molecular genetic analyses showed that half the variance in overall startle was due to additive genetic effects. No single nucleotide polymorphism was genome-wide significant, but GRIK3 did produce a significant effect when examined as part of a candidate gene set. In contrast, emotion modulation scores showed little evidence of heritability in either biometric or molecular genetic analyses. However, in a genome-wide scan, PARP14 did produce a significant effect for aversive modulation. We conclude that, although overall startle retains potential as an endophenotype, emotion-modulated startle does not. Twit Text FOAVip Heritability and molecular genetic basis of acoustic startle eye blink and affectively modulated startle response: A genome-wide association study ????Psychophysiology http://www.kidney.de/pget.php?&tw=1&pmid=25387708 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25387708 #FOAvip English Wikipedia <ref>{{Cite pmid|25387708}}</ref> Heritability and molecular genetic basis of acoustic startle eye blink and affectively modulated startle response: A genome-wide association study #MMPMID25387708 VAIDYANATHAN U; MALONE SM; MILLER MB; McGUE M; IACONO WG Psychophysiology 2014[Dec]; 51 (12): 1285-99 PMID25387708show ga Acoustic startle responses have been studied extensively in relation to individual differences and psychopathology. We examined three indices of the blink response in a picture-viewing paradigm?overall startle magnitude across all picture types, and aversive and pleasant modulation scores?in 3,323 twins and parents. Biometric models and molecular genetic analyses showed that half the variance in overall startle was due to additive genetic effects. No single nucleotide polymorphism was genome-wide significant, but GRIK3 did produce a significant effect when examined as part of a candidate gene set. In contrast, emotion modulation scores showed little evidence of heritability in either biometric or molecular genetic analyses. However, in a genome-wide scan, PARP14 did produce a significant effect for aversive modulation. We conclude that, although overall startle retains potential as an endophenotype, emotion-modulated startle does not. äHeritability and molecular genetic basis of acoustic startle eye blink(epmc).pdf DeepDyve Pubget Overpricing