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10.1111/psyp.12349 http://scihub22266oqcxt.onion/10.1111/psyp.12349 C4231532!4231532!25387709     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Psychophysiology 2014 ; 51 (12): 1300-8 Nephropedia Template TP {{tp|p=25387709|t=2014. Genetic associations of nonsynonymous exonic variants with psychophysiological endophenotypes |pdf=|usr=}}{{25387709}} gab.com Text Genetic associations of nonsynonymous exonic variants with psychophysiological endophenotypes JO: Psychophysiology http://www.kidney.de/pget.php?&tw=1&pmid=25387709 #FOAvip We mapped ~85,000 rare nonsynonymous exonic single nucleotide polymorphisms (SNPs) to 17 psychophysiological endophenotypes in 4,905 individuals, including antisaccade eye movements, resting EEG, P300 amplitude, electrodermal activity, affect-modulated startle eye blink. Nonsynonymous SNPs are predicted to directly change or disrupt proteins encoded by genes and are expected to have significant biological consequences. Most such variants are rare, and new technologies can efficiently assay them on a large scale. We assayed 247,870 mostly rare SNPs on an Illumina exome array. Approximately 85,000 of the SNPs were polymorphic, rare (MAF < .05), and nonsynonymous. Single variant association tests identified a SNP in the PARD3 gene associated with theta resting EEG power. The sequence kernel association test, a gene-based test, identified a gene PNPLA7 associated with pleasant difference startle, the difference in startle magnitude between pleasant and neutral images. No other single nonsynonymous variant, or gene-based group of variants, was strongly associated with any endophenotype. Twit Text FOAVip Genetic associations of nonsynonymous exonic variants with psychophysiological endophenotypes ????Psychophysiology http://www.kidney.de/pget.php?&tw=1&pmid=25387709 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25387709 #FOAvip English Wikipedia <ref>{{Cite pmid|25387709}}</ref> Genetic associations of nonsynonymous exonic variants with psychophysiological endophenotypes #MMPMID25387709 Vrieze SI; Malone SM; Pankratz N; Vaidyanathan U; Miller MB; Kang HM; McGue M; Abecasis G; Iacono WG Psychophysiology 2014[Dec]; 51 (12): 1300-8 PMID25387709show ga We mapped ~85,000 rare nonsynonymous exonic single nucleotide polymorphisms (SNPs) to 17 psychophysiological endophenotypes in 4,905 individuals, including antisaccade eye movements, resting EEG, P300 amplitude, electrodermal activity, affect-modulated startle eye blink. Nonsynonymous SNPs are predicted to directly change or disrupt proteins encoded by genes and are expected to have significant biological consequences. Most such variants are rare, and new technologies can efficiently assay them on a large scale. We assayed 247,870 mostly rare SNPs on an Illumina exome array. Approximately 85,000 of the SNPs were polymorphic, rare (MAF < .05), and nonsynonymous. Single variant association tests identified a SNP in the PARD3 gene associated with theta resting EEG power. The sequence kernel association test, a gene-based test, identified a gene PNPLA7 associated with pleasant difference startle, the difference in startle magnitude between pleasant and neutral images. No other single nonsynonymous variant, or gene-based group of variants, was strongly associated with any endophenotype. äGenetic associations of nonsynonymous exonic variants with psychophysi(epmc).pdf DeepDyve Pubget Overpricing