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10.1111/psyp.12343 http://scihub22266oqcxt.onion/10.1111/psyp.12343 C4231489!4231489!25387703     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Psychophysiology 2014 ; 51 (12): 1207-24 Nephropedia Template TP {{tp|p=25387703|t=2014. Genome-wide scans of genetic variants for psychophysiological endophenotypes: A methodological overview |pdf=|usr=}}{{25387703}} gab.com Text Genome-wide scans of genetic variants for psychophysiological endophenotypes: A methodological overview JO: Psychophysiology http://www.kidney.de/pget.php?&tw=1&pmid=25387703 #FOAvip This article provides an introductory overview of the investigative strategy employed to evaluate the genetic basis of 17 endophenotypes examined as part of a 20-year data collection effort from the Minnesota Center for Twin and Family Research. Included are characterization of the study samples, descriptive statistics for key properties of the psychophysiological measures, and rationale behind the steps taken in the molecular genetic study design. The statistical approach included (a) biometric analysis of twin and family data, (b) heritability analysis using 527,829 single nucleotide polymorphisms (SNPs), (c) genome-wide association analysis of these SNPs and 17,601 autosomal genes, (d) follow-up analyses of candidate SNPs and genes hypothesized to have an association with each endophenotype, (e) rare variant analysis of nonsynonymous SNPs in the exome, and (f) whole genome sequencing association analysis using 27 million genetic variants. These methods were used in the accompanying empirical articles comprising this special issue, Genome-Wide Scans of Genetic Variants for Psychophysiological Endophenotypes. Twit Text FOAVip Genome-wide scans of genetic variants for psychophysiological endophenotypes: A methodological overview ????Psychophysiology http://www.kidney.de/pget.php?&tw=1&pmid=25387703 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25387703 #FOAvip English Wikipedia <ref>{{Cite pmid|25387703}}</ref> Genome-wide scans of genetic variants for psychophysiological endophenotypes: A methodological overview #MMPMID25387703 IACONO WG; MALONE SM; VAIDYANATHAN U; VRIEZE SI Psychophysiology 2014[Dec]; 51 (12): 1207-24 PMID25387703show ga This article provides an introductory overview of the investigative strategy employed to evaluate the genetic basis of 17 endophenotypes examined as part of a 20-year data collection effort from the Minnesota Center for Twin and Family Research. Included are characterization of the study samples, descriptive statistics for key properties of the psychophysiological measures, and rationale behind the steps taken in the molecular genetic study design. The statistical approach included (a) biometric analysis of twin and family data, (b) heritability analysis using 527,829 single nucleotide polymorphisms (SNPs), (c) genome-wide association analysis of these SNPs and 17,601 autosomal genes, (d) follow-up analyses of candidate SNPs and genes hypothesized to have an association with each endophenotype, (e) rare variant analysis of nonsynonymous SNPs in the exome, and (f) whole genome sequencing association analysis using 27 million genetic variants. These methods were used in the accompanying empirical articles comprising this special issue, Genome-Wide Scans of Genetic Variants for Psychophysiological Endophenotypes. äGenome-wide scans of genetic variants for psychophysiological endophen(epmc).pdf DeepDyve Pubget Overpricing