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10.1073/pnas.1412998111 http://scihub22266oqcxt.onion/10.1073/pnas.1412998111 C4217451!4217451!25313083     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2014 ; 111 (43): 15508-13 Nephropedia Template TP {{tp|p=25313083|t=2014. TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation |pdf=|usr=}}{{25313083}} gab.com Text TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25313083 #FOAvip Dendritic cells (DCs) ingest bacteria at sites of infection, signal the presence of invaders via phagosomal Toll-like receptors (TLRs), and present bacterial antigens to the adaptive immune system. We show that TLR signaling from maturing phagosomes in DCs stimulates the formation of membrane tubules that facilitate content transfer with other signaling phagosomes and thereby promote optimal presentation of phagocytosed antigens. The phagosomal tubules are thus functionally distinct from those of lysosomes and link innate immune signaling to enhanced adaptive immune responses. Twit Text FOAVip TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25313083 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25313083 #FOAvip English Wikipedia <ref>{{Cite pmid|25313083}}</ref> TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation #MMPMID25313083 Mantegazza AR; Zajac AL; Twelvetrees A; Holzbaur ELF; Amigorena S; Marks MS Proc Natl Acad Sci U S A 2014[Oct]; 111 (43): 15508-13 PMID25313083show ga Dendritic cells (DCs) ingest bacteria at sites of infection, signal the presence of invaders via phagosomal Toll-like receptors (TLRs), and present bacterial antigens to the adaptive immune system. We show that TLR signaling from maturing phagosomes in DCs stimulates the formation of membrane tubules that facilitate content transfer with other signaling phagosomes and thereby promote optimal presentation of phagocytosed antigens. The phagosomal tubules are thus functionally distinct from those of lysosomes and link innate immune signaling to enhanced adaptive immune responses. äTLR-dependent phagosome tubulation in dendritic cells promotes phagoso(epmc).pdf DeepDyve Pubget Overpricing