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10.1111/imr.12186 http://scihub22266oqcxt.onion/10.1111/imr.12186 C4216679!4216679!24942680     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Immunol+Rev 2014 ; 260 (1): 35-49 Nephropedia Template TP {{tp|p=24942680|t=2014. Anatomical localization of commensal bacteria in immune cell homeostasis and disease |pdf=|usr=}}{{24942680}} gab.com Text Anatomical localization of commensal bacteria in immune cell homeostasis and disease JO: Immunol Rev http://www.kidney.de/pget.php?&tw=1&pmid=24942680 #FOAvip The mammalian gastro-intestinal (GI) tract is colonized by trillions of beneficial commensal bacteria that are essential for promoting normal intestinal physiology. While the majority of commensal bacteria are found in the intestinal lumen, many species have also adapted to colonize different anatomical locations in the intestine, including the surface of intestinal epithelial cells (IECs) and the interior of gut-associated lymphoid tissues. These distinct tissue localization patterns permit unique interactions with the mammalian immune system and collectively influence intestinal immune cell homeostasis. Conversely, dysregulated localization of commensal bacteria can lead to inappropriate activation of the immune system and is associated with numerous chronic infectious, inflammatory and metabolic diseases. Therefore, regulatory mechanisms that control proper anatomical containment of commensal bacteria are essential to maintain tissue homeostasis and limit pathology. In this review, we propose that commensal bacteria associated with the mammalian GI tract can be anatomically defined as (i) luminal, (ii) epithelial-associated or (iii) lymphoid tissue-resident, and we will discuss the role and regulation of these microbial populations in health and disease. Twit Text FOAVip Anatomical localization of commensal bacteria in immune cell homeostasis and disease ????Immunol Rev http://www.kidney.de/pget.php?&tw=1&pmid=24942680 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24942680 #FOAvip English Wikipedia <ref>{{Cite pmid|24942680}}</ref> Anatomical localization of commensal bacteria in immune cell homeostasis and disease #MMPMID24942680 Fung TC; Artis D; Sonnenberg GF Immunol Rev 2014[Jul]; 260 (1): 35-49 PMID24942680show ga The mammalian gastro-intestinal (GI) tract is colonized by trillions of beneficial commensal bacteria that are essential for promoting normal intestinal physiology. While the majority of commensal bacteria are found in the intestinal lumen, many species have also adapted to colonize different anatomical locations in the intestine, including the surface of intestinal epithelial cells (IECs) and the interior of gut-associated lymphoid tissues. These distinct tissue localization patterns permit unique interactions with the mammalian immune system and collectively influence intestinal immune cell homeostasis. Conversely, dysregulated localization of commensal bacteria can lead to inappropriate activation of the immune system and is associated with numerous chronic infectious, inflammatory and metabolic diseases. Therefore, regulatory mechanisms that control proper anatomical containment of commensal bacteria are essential to maintain tissue homeostasis and limit pathology. In this review, we propose that commensal bacteria associated with the mammalian GI tract can be anatomically defined as (i) luminal, (ii) epithelial-associated or (iii) lymphoid tissue-resident, and we will discuss the role and regulation of these microbial populations in health and disease. äAnatomical localization of commensal bacteria in immune cell homeostas(epmc).pdf DeepDyve Pubget Overpricing