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10.1098/rstb.2013.0537

http://scihub22266oqcxt.onion/10.1098/rstb.2013.0537
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C4216460!4216460!25349446
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suck abstract from ncbi


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pmid25349446      Philos+Trans+R+Soc+Lond+B+Biol+Sci 2014 ; 369 (1657): ä
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  • Primitive endoderm differentiation: from specification to epithelium formation #MMPMID25349446
  • Hermitte S; Chazaud C
  • Philos Trans R Soc Lond B Biol Sci 2014[Dec]; 369 (1657): ä PMID25349446show ga
  • In amniotes, primitive endoderm (PrE) plays important roles not only for nutrient support but also as an inductive tissue required for embryo patterning. PrE is an epithelial monolayer that is visible shortly before embryo implantation and is one of the first three cell lineages produced by the embryo. We review here the molecular mechanisms that have been uncovered during the past 10 years on PrE and epiblast cell lineage specification within the inner cell mass of the blastocyst and on their subsequent steps of differentiation.
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