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10.1083/jcb.201408039

http://scihub22266oqcxt.onion/10.1083/jcb.201408039
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C4210441!4210441!25349257
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suck abstract from ncbi

pmid25349257      J+Cell+Biol 2014 ; 207 (2): 171-9
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  • The cell biology of planar cell polarity #MMPMID25349257
  • Devenport D
  • J Cell Biol 2014[Oct]; 207 (2): 171-9 PMID25349257show ga
  • Planar cell polarity (PCP) refers to the coordinated alignment of cell polarity across the tissue plane. Key to the establishment of PCP is asymmetric partitioning of cortical PCP components and intercellular communication to coordinate polarity between neighboring cells. Recent progress has been made toward understanding how protein transport, endocytosis, and intercellular interactions contribute to asymmetric PCP protein localization. Additionally, the functions of gradients and mechanical forces as global cues that bias PCP orientation are beginning to be elucidated. Together, these findings are shedding light on how global cues integrate with local cell interactions to organize cellular polarity at the tissue level.
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