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10.1073/pnas.1416714111 http://scihub22266oqcxt.onion/10.1073/pnas.1416714111 C4210310!4210310!25294929     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2014 ; 111 (42): 15178-83 Nephropedia Template TP {{tp|p=25294929|t=2014. Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells |pdf=|usr=}}{{25294929}} gab.com Text Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25294929 #FOAvip The skin develops antigen-specific immune response, called ?allergic contact dermatitis? in humans and ?contact hypersensitivity? (CHS) in mice. IL-1 family member IL-37 expression in transgenic mice (IL-37tg) inhibits innate immune responses. In this study we show that DCs from IL-37tg mice exhibit diminished CHS response to an antigen-specific exposure. Although DCs from IL-37tg mice maintain migratory capacity to lymph nodes, they fail to activate T cells effectively; instead, they promote generation of T regulatory cells, a characteristic of semimature DCs that dampen adaptive immune response. Thus, IL-37 emerges as an inhibitor of adaptive immunity. Twit Text FOAVip Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=25294929 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25294929 #FOAvip English Wikipedia <ref>{{Cite pmid|25294929}}</ref> Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells #MMPMID25294929 Luo Y; Cai X; Liu S; Wang S; Nold-Petry CA; Nold MF; Bufler P; Norris D; Dinarello CA; Fujita M Proc Natl Acad Sci U S A 2014[Oct]; 111 (42): 15178-83 PMID25294929show ga The skin develops antigen-specific immune response, called ?allergic contact dermatitis? in humans and ?contact hypersensitivity? (CHS) in mice. IL-1 family member IL-37 expression in transgenic mice (IL-37tg) inhibits innate immune responses. In this study we show that DCs from IL-37tg mice exhibit diminished CHS response to an antigen-specific exposure. Although DCs from IL-37tg mice maintain migratory capacity to lymph nodes, they fail to activate T cells effectively; instead, they promote generation of T regulatory cells, a characteristic of semimature DCs that dampen adaptive immune response. Thus, IL-37 emerges as an inhibitor of adaptive immunity. äSuppression of antigen-specific adaptive immunity by IL-37 via inducti(epmc).pdf DeepDyve Pubget Overpricing