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Role for LSM genes in the regulation of circadian rhythms #MMPMID25288739
Proc Natl Acad Sci U S A 2014[Oct]; 111 (42): 15166-71 PMID25288739show ga
There is increasing evidence that previously considered core constituents of multi-subunit complexes involved in RNA processing play regulatory rather than passive roles in the control of gene expression, but specific signaling pathways in which they participate are not known. Here we show that SM-like (LSM) genes, which encode core components of the spliceosome, are regulated by the circadian clock and control clock function in plants and mammals, revealing convergent evolutionary mechanisms mediating posttranscriptional regulation of circadian networks across kingdoms.