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suck abstract from ncbi


10.1073/pnas.1405209111

http://scihub22266oqcxt.onion/10.1073/pnas.1405209111
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C4210000!4210000!25246549
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suck abstract from ncbi


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pmid25246549      Proc+Natl+Acad+Sci+U+S+A 2014 ; 111 (40): 14366-71
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  • Mechanochemical actuators of embryonic epithelial contractility #MMPMID25246549
  • Kim Y; Hazar M; Vijayraghavan DS; Song J; Jackson TR; Joshi SD; Messner WC; Davidson LA; LeDuc PR
  • Proc Natl Acad Sci U S A 2014[Oct]; 111 (40): 14366-71 PMID25246549show ga
  • This study shows how cell contractility is triggered within an embryonic epithelial sheet by local ligand stimulation and coordinates a long-range contraction response. The stimulation?response circuit exposed here provides a better understanding of how morphogenetic processes integrate responses to stimulation and how intercellular responses are transmitted across multiple cells. Understanding the systems-level behavior of biological signaling networks may allow us to control biological actuators with engineered spatiotemporal stimulation. Our findings will provide a better understanding of contractility-dependent morphogenetic movements as well as the intercellular communication pathways critical during developmental biology, synthetic morphogenesis, and multicellular mechanotransduction signaling.
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