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10.1101/cshperspect.a013912 http://scihub22266oqcxt.onion/10.1101/cshperspect.a013912 C4208706!4208706 !25368013     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25368013 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cold+Spring+Harb+Perspect+Med 2014 ; 4 (11 ): a013912 Nephropedia Template TP {{tp|p=25368013 |t=2014. How to make a heart valve: from embryonic development to bioengineering of living valve substitutes |pdf=|usr=}}{{25368013 }} gab.com Text How to make a heart valve: from embryonic development to bioengineering of living valve substitutes JO: Cold Spring Harb Perspect Med http://www.kidney.de/pget.php?&tw=1&pmid=25368013 #FOAvip Cardiac valve disease is a significant cause of ill health and death worldwide, and valve replacement remains one of the most common cardiac interventions in high-income economies. Despite major advances in surgical treatment, long-term therapy remains inadequate because none of the current valve substitutes have the potential for remodeling, regeneration, and growth of native structures. Valve development is coordinated by a complex interplay of signaling pathways and environmental cues that cause disease when perturbed. Cardiac valves develop from endocardial cushions that become populated by valve precursor mesenchyme formed by an epithelial-mesenchymal transition (EMT). The mesenchymal precursors, subsequently, undergo directed growth, characterized by cellular compartmentalization and layering of a structured extracellular matrix (ECM). Knowledge gained from research into the development of cardiac valves is driving exploration into valve biomechanics and tissue engineering directed at creating novel valve substitutes endowed with native form and function. Twit Text FOAVip How to make a heart valve: from embryonic development to bioengineering of living valve substitutes ????Cold Spring Harb Perspect Med http://www.kidney.de/pget.php?&tw=1&pmid=25368013 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25368013 #FOAvip English Wikipedia <ref>{{Cite pmid|25368013 }}</ref> How to make a heart valve: from embryonic development to bioengineering of living valve substitutes #MMPMID25368013 MacGrogan D ; Luxán G ; Driessen-Mol A ; Bouten C ; Baaijens F ; de la Pompa JL Cold Spring Harb Perspect Med 2014[Nov]; 4 (11 ): a013912 PMID25368013 show ga Cardiac valve disease is a significant cause of ill health and death worldwide, and valve replacement remains one of the most common cardiac interventions in high-income economies. Despite major advances in surgical treatment, long-term therapy remains inadequate because none of the current valve substitutes have the potential for remodeling, regeneration, and growth of native structures. Valve development is coordinated by a complex interplay of signaling pathways and environmental cues that cause disease when perturbed. Cardiac valves develop from endocardial cushions that become populated by valve precursor mesenchyme formed by an epithelial-mesenchymal transition (EMT). The mesenchymal precursors, subsequently, undergo directed growth, characterized by cellular compartmentalization and layering of a structured extracellular matrix (ECM). Knowledge gained from research into the development of cardiac valves is driving exploration into valve biomechanics and tissue engineering directed at creating novel valve substitutes endowed with native form and function. |*Heart Valve Prosthesis [MESH] |Animals [MESH] |Extracellular Matrix/physiology [MESH] |Heart Valves/anatomy & histology/cytology/*embryology [MESH] |Humans [MESH] |Morphogenesis/physiology [MESH] |Tissue Engineering [MESH]How to make a heart valve: from embryonic development to bioengineerin(epmc).pdf DeepDyve Pubget Overpricing