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10.1111/ajt.12906

http://scihub22266oqcxt.onion/10.1111/ajt.12906
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C4205186!4205186!25293374
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suck abstract from ncbi


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pmid25293374      Am+J+Transplant 2014 ; 14 (11): 2535-44
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  • Emotional Well-being of Living Kidney Donors: Findings from the RELIVE Study #MMPMID25293374
  • Jowsey S; Jacobs C; Gross C; Hong B; Messersmith E; Gillespie B; Beebe T; Kew C; Matas A; Yusen R; Hill-Callahan M; Odim J; Taler S
  • Am J Transplant 2014[Nov]; 14 (11): 2535-44 PMID25293374show ga
  • Following kidney donation, short-term quality of life outcomes compare favorably to US normative data but long-term effects on mood are not known. In the Renal and Lung Living Donors Evaluation Study (RELIVE), records from donations performed 1963?2005 were reviewed for depression and antidepressant use pre-donation. Post-donation, in a cross-sectional cohort design 2010?2012, donors completed the Patient Health Questionnaire (PHQ-9) depression screening instrument, the Life Orientation Test-Revised, 36-Item Short Form Health Survey, and donation experience questions. Of 6,909 eligible donors, 3,470 were contacted and 2,455 participated (71%). The percent with depressive symptoms (8%; PHQ-9>10) was similar to National Health and Nutrition Examination Survey participants (7%, p=0.30). Pre-donation psychiatric disorders were more common in unrelated than related donors (p=0.05). Post-donation predictors of depressive symptoms included non-white race OR=2.00, p=0.020), younger age at donation (OR=1.33 per 10 years, p-0.002), longer recovery time from donation (OR=1.74, p=0.0009), greater financial burden (OR=1.32, p=0.013), and feeling morally obligated to donate (OR=1.23, p=0.003). While cross-sectional prevalence of depression is comparable to population normative data, some factors identifiable around time of donation, including longer recovery, financial stressors, younger age, and moral obligation to donate may identify donors more likely to develop future depression, providing an opportunity for intervention.
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