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10.1084/jem.20140338

http://scihub22266oqcxt.onion/10.1084/jem.20140338
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C4203942!4203942!25288398
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suck abstract from ncbi


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pmid25288398      J+Exp+Med 2014 ; 211 (11): 2183-98
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  • The miR-155?PU 1 axis acts on Pax5 to enable efficient terminal B cell differentiation #MMPMID25288398
  • Lu D; Nakagawa R; Lazzaro S; Staudacher P; Abreu-Goodger C; Henley T; Boiani S; Leyland R; Galloway A; Andrews S; Butcher G; Nutt SL; Turner M; Vigorito E
  • J Exp Med 2014[Oct]; 211 (11): 2183-98 PMID25288398show ga
  • Lu et al. disrupt the interaction between miR-155 and the transcription factor PU.1 by specifically removing miR-155?binding site from PU.1 mRNA in mice. They show that this interaction is required for plasma cell formation and extrafollicular response to immunization in vivo.
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