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10.4161/auto.29395 http://scihub22266oqcxt.onion/10.4161/auto.29395 C4203544!4203544!24915298     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Autophagy 2014 ; 10 (7): 1154-66 Nephropedia Template TP {{tp|p=24915298|t=2014. The autophagic roles of Rab small GTPases and their upstream regulators: A review |pdf=|usr=}}{{24915298}} gab.com Text The autophagic roles of Rab small GTPases and their upstream regulators: A review JO: Autophagy http://www.kidney.de/pget.php?&tw=1&pmid=24915298 #FOAvip Macroautophagy is an evolutionarily conserved degradative process of eukaryotic cells. Double-membrane vesicles called autophagosomes sequester portions of cytoplasm and undergo fusion with the endolysosomal pathway in order to degrade their content. There is growing evidence that members of the small GTPase RAB protein family?the well-known regulators of membrane trafficking and fusion events?play key roles in the regulation of the autophagic process. Despite numerous studies focusing on the functions of RAB proteins in autophagy, the importance of their upstream regulators in this process emerged only in the past few years. In this review, we summarize recent advances on the effects of RABs and their upstream modulators in the regulation of autophagy. Moreover, we discuss how impairment of these proteins alters the autophagic process leading to several generally known human diseases. Twit Text FOAVip The autophagic roles of Rab small GTPases and their upstream regulators: A review ????Autophagy http://www.kidney.de/pget.php?&tw=1&pmid=24915298 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24915298 #FOAvip English Wikipedia <ref>{{Cite pmid|24915298}}</ref> The autophagic roles of Rab small GTPases and their upstream regulators: A review #MMPMID24915298 Szatmári Z; Sass M Autophagy 2014[Jul]; 10 (7): 1154-66 PMID24915298show ga Macroautophagy is an evolutionarily conserved degradative process of eukaryotic cells. Double-membrane vesicles called autophagosomes sequester portions of cytoplasm and undergo fusion with the endolysosomal pathway in order to degrade their content. There is growing evidence that members of the small GTPase RAB protein family?the well-known regulators of membrane trafficking and fusion events?play key roles in the regulation of the autophagic process. Despite numerous studies focusing on the functions of RAB proteins in autophagy, the importance of their upstream regulators in this process emerged only in the past few years. In this review, we summarize recent advances on the effects of RABs and their upstream modulators in the regulation of autophagy. Moreover, we discuss how impairment of these proteins alters the autophagic process leading to several generally known human diseases. äThe autophagic roles of Rab small GTPases and their upstream regulator(epmc).pdf DeepDyve Pubget Overpricing