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Clinical examples of 3D dose distribution reconstruction, based on the actual MLC
leaves movement, for dynamic treatment techniques
#MMPMID25337416
Osewski W
; Dolla L
; Radwan M
; Szlag M
; Rutkowski R
; Smoli?ska B
; Slosarek K
Rep Pract Oncol Radiother
2014[Nov]; 19
(6
): 420-7
PMID25337416
show ga
AIM: To present practical examples of our new algorithm for reconstruction of 3D
dose distribution, based on the actual MLC leaf movement. BACKGROUND: DynaLog and
RTplan files were used by DDcon software to prepare a new RTplan file for dose
distribution reconstruction. MATERIALS AND METHODS: FOUR DIFFERENT CLINICALLY
RELEVANT SCENARIOS WERE USED TO ASSESS THE FEASIBILITY OF THE PROPOSED NEW
APPROACH: (1) Reconstruction of whole treatment sessions for prostate cancer; (2)
Reconstruction of IMRT verification treatment plan; (3) Dose reconstruction in
breast cancer; (4) Reconstruction of interrupted arc and complementary plan for
an interrupted VMAT treatment session of prostate cancer. The applied
reconstruction method was validated by comparing reconstructed and measured
fluence maps. For all statistical analysis, the U Mann-Whitney test was used.
RESULTS: In the first two and the fourth cases, there were no statistically
significant differences between the planned and reconstructed dose distribution
(p = 0.910, p = 0.975, p = 0.893, respectively). In the third case the
differences were statistically significant (p = 0.015). Treatment plan had to be
reconstructed. CONCLUSION: Developed dose distribution reconstruction algorithm
presents a very useful QA tool. It provides means for 3D dose distribution
verification in patient volume and allows to evaluate the influence of actual MLC
leaf motion on the dose distribution.
free
free
free
