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10.4161/fly.28063 http://scihub22266oqcxt.onion/10.4161/fly.28063 C4197016!4197016!25483250     free     free     free       Fly+(Austin) 2014 ; 8 (2): 63-7 Nephropedia Template TP {{tp|p=25483250|t=2014. Nuclear lamina builds tissues from the stem cell niche |pdf=|usr=}}{{25483250}} gab.com Text Nuclear lamina builds tissues from the stem cell niche JO: Fly (Austin) http://www.kidney.de/pget.php?&tw=1&pmid=25483250 #FOAvip Recent studies show that nuclear lamins, the type V intermediate filament proteins, are required for proper building of at least some organs. As the major structural components of the nuclear lamina found underneath the inner nuclear membranes, lamins are ubiquitously expressed in all animal cells. How the broadly expressed lamins support the building of specific tissues is not understood. By studying Drosophila testis, we have uncovered a mechanism by which lamin-B functions in the cyst stem cell (CySC) and its differentiated cyst cell, the cell types known to form the niche/microenvironment for the germline stem cells (GSC) and the developing germ line, to ensure testis organogenesis 1. In this extra view, we discuss some remaining questions and the implications of our findings in the understanding of how the ubiquitous nuclear lamina regulates tissue building in a context-dependent manner. Twit Text FOAVip Nuclear lamina builds tissues from the stem cell niche ????Fly (Austin) http://www.kidney.de/pget.php?&tw=1&pmid=25483250 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25483250 #FOAvip English Wikipedia <ref>{{Cite pmid|25483250}}</ref> Nuclear lamina builds tissues from the stem cell niche #MMPMID25483250 Chen H; Zheng Y Fly (Austin) 2014[Apr]; 8 (2): 63-7 PMID25483250show ga Recent studies show that nuclear lamins, the type V intermediate filament proteins, are required for proper building of at least some organs. As the major structural components of the nuclear lamina found underneath the inner nuclear membranes, lamins are ubiquitously expressed in all animal cells. How the broadly expressed lamins support the building of specific tissues is not understood. By studying Drosophila testis, we have uncovered a mechanism by which lamin-B functions in the cyst stem cell (CySC) and its differentiated cyst cell, the cell types known to form the niche/microenvironment for the germline stem cells (GSC) and the developing germ line, to ensure testis organogenesis 1. In this extra view, we discuss some remaining questions and the implications of our findings in the understanding of how the ubiquitous nuclear lamina regulates tissue building in a context-dependent manner. äNuclear lamina builds tissues from the stem cell niche (epmc).pdf DeepDyve Pubget Overpricing