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10.1128/AAC.02784-14

http://scihub22266oqcxt.onion/10.1128/AAC.02784-14
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C4187991!4187991!25092692
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suck abstract from ncbi


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pmid25092692      Antimicrob+Agents+Chemother 2014 ; 58 (10): 6297-301
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  • Linezolid Manifests a Rapid and Dramatic Therapeutic Effect for Patients with Life-Threatening Tuberculous Meningitis #MMPMID25092692
  • Sun F; Ruan Q; Wang J; Chen S; Jin J; Shao L; Zhang Y; Zhang W
  • Antimicrob Agents Chemother 2014[Oct]; 58 (10): 6297-301 PMID25092692show ga
  • We conducted a retrospective cohort study of patients with MRC grade II/III tuberculous meningitis (TBM) who accepted a background antitubercular regimen (BR) with or without linezolid (LZD). At the 4th week, the LZD-BR group achieved a faster and higher percentage of Glasgow coma scale recovery and temperature recovery, a higher cerebrospinal fluid (CSF)/blood glucose ratio, and lower CSF white blood cell counts than did the BR group. Short-term linezolid supplementation may be a more effective treatment for life-threatening TBM.
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