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10.1016/j.visres.2014.07.008

http://scihub22266oqcxt.onion/10.1016/j.visres.2014.07.008
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C4180079!4180079!25088242
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suck abstract from ncbi


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pmid25088242      Vision+Res 2014 ; 102 (ä): 64-70
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  • Vergence Eye Movements in Patients with Schizophrenia #MMPMID25088242
  • Bolding M; Lahti A; White D; Moore C; Gurler D; Gawne T; Gamlin P
  • Vision Res 2014[Sep]; 102 (ä): 64-70 PMID25088242show ga
  • Previous studies have shown that smooth pursuit eye movements are impaired in patients with schizophrenia. However, under normal viewing conditions, targets move not only in the frontoparallel plane but also in depth, and tracking them requires both smooth pursuit and vergence eye movements. Although previous studies in humans and non-human primates suggest that these two eye movement subsystems are relatively independent of one another, to our knowledge, there have been no prior studies of vergence tracking behavior in patients with schizophrenia. Therefore, we have investigated these eye movements in patients with schizophrenia and in healthy controls.We found that patients with schizophrenia exhibited substantially lower gains compared to healthy controls during vergence tracking at all tested speeds (e.g. 0.25 Hz vergence tracking mean gain of 0.59 vs. 0.86).Further, consistent with previous reports, patients with schizophrenia exhibited significantly lower gains than healthy controls during smooth pursuit at higher target speeds (e.g. 0.5 Hz smooth pursuit mean gain of 0.64 vs. 0.73). In addition, there was a modest (r?0.5), but significant, correlation between smooth pursuit and vergence tracking performance in patients with schizophrenia.Our observations clearly demonstrate substantial vergence tracking deficits in patients with schizophrenia. In these patients, deficits for smooth pursuit and vergence tracking are partially correlated suggesting overlap in the central control of smooth pursuit and vergence eye movements.
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