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10.1016/j.bbagrm.2014.05.013

http://scihub22266oqcxt.onion/10.1016/j.bbagrm.2014.05.013
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C4177946!4177946!24863160
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suck abstract from ncbi


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pmid24863160      Biochim+Biophys+Acta 2014 ; 1839 (10): 931-8
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  • Common themes and differences in SAM recognition among SAM riboswitches #MMPMID24863160
  • Price IR; Grigg JC; Ke A
  • Biochim Biophys Acta 2014[Oct]; 1839 (10): 931-8 PMID24863160show ga
  • The recent discovery of short cis-acting RNA elements termed riboswitches has caused a paradigm shift in our understanding of genetic regulatory mechanisms. The three distinct superfamilies of S-adenosyl-L-methionine (SAM) riboswitches are the most commonly found riboswitch classes in nature. These RNAs represent three independent evolutionary solutions to achieve specific SAM recognition. This review summarizes research on 1) modes of gene regulatory mechanisms, 2) common themes and differences in ligand recognition, and 3) ligand-induced conformational dynamics among SAM riboswitch families. The body of work on the SAM riboswitch families constitutes a useful primer to the topic of gene regulatory RNAs as a whole.
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