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10.1074/jbc.M114.590034 http://scihub22266oqcxt.onion/10.1074/jbc.M114.590034 C4176236!4176236!25107908     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Biol+Chem 2014 ; 289 (38): 26277-89 Nephropedia Template TP {{tp|p=25107908|t=2014. A Systems Biology Analysis of Apoptosome Formation and Apoptosis Execution Supports Allosteric Procaspase-9 Activation* |pdf=|usr=}}{{25107908}} gab.com Text A Systems Biology Analysis of Apoptosome Formation and Apoptosis Execution Supports Allosteric Procaspase-9 Activation* JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=25107908 #FOAvip Background: Mathematical simulations of apoptosome formation and mechanisms of caspase-9 activation were conducted and validated against experimental data.Results: Only simulations that assume allosteric caspase-9 activation can accurately reproduce all experimental data.Conclusion: A mechanism of allosteric caspase-9 activation is favored over homodimerization-based activation.Significance: Our findings challenge the dogma that all initiator caspases are activated by homodimerization. Twit Text FOAVip A Systems Biology Analysis of Apoptosome Formation and Apoptosis Execution Supports Allosteric Procaspase-9 Activation* ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=25107908 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25107908 #FOAvip English Wikipedia <ref>{{Cite pmid|25107908}}</ref> A Systems Biology Analysis of Apoptosome Formation and Apoptosis Execution Supports Allosteric Procaspase-9 Activation* #MMPMID25107908 Würstle ML; Rehm M J Biol Chem 2014[Sep]; 289 (38): 26277-89 PMID25107908show ga Background: Mathematical simulations of apoptosome formation and mechanisms of caspase-9 activation were conducted and validated against experimental data.Results: Only simulations that assume allosteric caspase-9 activation can accurately reproduce all experimental data.Conclusion: A mechanism of allosteric caspase-9 activation is favored over homodimerization-based activation.Significance: Our findings challenge the dogma that all initiator caspases are activated by homodimerization. äA Systems Biology Analysis of Apoptosome Formation and Apoptosis Execu(epmc).pdf DeepDyve Pubget Overpricing