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10.1039/C4AY01534G

http://scihub22266oqcxt.onion/10.1039/C4AY01534G
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C4175734!4175734!25267929
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suck abstract from ncbi


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pmid25267929      Anal+Methods 2014 ; 6 (20): 8180-6
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  • A Simple Microfluidic Electrochemical HPLC Detector for Quantifying Fenton Reactivity from Welding Fumes #MMPMID25267929
  • Pluangklang T; Wydallis JB; Cate DM; Nacapricha D; Henry CS
  • Anal Methods 2014[Oct]; 6 (20): 8180-6 PMID25267929show ga
  • Development and characterization of a simple microfluidic electrochemical flow cell that can be coupled with HPLC to enable dual absorbance/electrochemical detection is described. Coupling absorbance and electrochemical detection increases the information that can be gathered from a single injection, but a second (typically expensive) detection system is required. Here, an inexpensive, customizable microfluidic electrochemical detector is coupled in series with a commercial HPLC/UV system. The microfluidic device is made from poly(dimethylsiloxane) and contains carbon paste electrodes. To demonstrate the utility of this dual-detection system, the reaction products of the radical scavenging agent salicylic acid and hydroxyl radical generated by Fenton chemistry were analyzed. The dual-detection system was used to quantify 2,5-dihydroxybenzoic acid, 2,3-dihydroxybenzoic acid, and catechol produced by the addition of H2O2 to filter samples of welding fumes. Measurement recovery was high, with percent recoveries between 97-102%, 92-103%, and 95-103% for 2,5-dihydroxybenzoic acid, 2,3-dihydroxybenzoic acid, and catechol, respectively, for control samples. The methods described in this work are simple, reliable, and can inexpensively couple electrochemical detection to HPLC-UV systems.
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