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10.1369/0022155414532293 http://scihub22266oqcxt.onion/10.1369/0022155414532293 C4174630!4174630!24700756     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Histochem+Cytochem 2014 ; 62 (6): 460-70 Nephropedia Template TP {{tp|p=24700756|t=2014. Characterization of Leukocyte Formin FMNL1 Expression in Human Tissues |pdf=|usr=}}{{24700756}} gab.com Text Characterization of Leukocyte Formin FMNL1 Expression in Human Tissues JO: J Histochem Cytochem http://www.kidney.de/pget.php?&tw=1&pmid=24700756 #FOAvip Formins are cytoskeleton regulating proteins characterized by a common FH2 structural domain. As key players in the assembly of actin filaments, formins direct dynamic cytoskeletal processes that influence cell shape, movement and adhesion. The large number of formin genes, fifteen in the human, suggests distinct tasks and expression patterns for individual family members, in addition to overlapping functions. Several formins have been associated with invasive cell properties in experimental models, linking them to cancer biology. One example is FMNL1, which is considered to be a leukocyte formin and is known to be overexpressed in lymphomas. Studies on FMNL1 and many other formins have been hampered by a lack of research tools, especially antibodies suitable for staining paraffin-embedded formalin-fixed tissues. Here we characterize, using bioinformatics tools and a validated antibody, the expression pattern of FMNL1 in human tissues and study its subcellular distribution. Our results indicate that FMNL1 expression is not restricted to hematopoietic tissues and that neoexpression of FMNL1 can be seen in epithelial cancer. Twit Text FOAVip Characterization of Leukocyte Formin FMNL1 Expression in Human Tissues ????J Histochem Cytochem http://www.kidney.de/pget.php?&tw=1&pmid=24700756 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24700756 #FOAvip English Wikipedia <ref>{{Cite pmid|24700756}}</ref> Characterization of Leukocyte Formin FMNL1 Expression in Human Tissues #MMPMID24700756 Gardberg M; Heuser VD; Iljin K; Kampf C; Uhlen M; Carpén O J Histochem Cytochem 2014[Jun]; 62 (6): 460-70 PMID24700756show ga Formins are cytoskeleton regulating proteins characterized by a common FH2 structural domain. As key players in the assembly of actin filaments, formins direct dynamic cytoskeletal processes that influence cell shape, movement and adhesion. The large number of formin genes, fifteen in the human, suggests distinct tasks and expression patterns for individual family members, in addition to overlapping functions. Several formins have been associated with invasive cell properties in experimental models, linking them to cancer biology. One example is FMNL1, which is considered to be a leukocyte formin and is known to be overexpressed in lymphomas. Studies on FMNL1 and many other formins have been hampered by a lack of research tools, especially antibodies suitable for staining paraffin-embedded formalin-fixed tissues. Here we characterize, using bioinformatics tools and a validated antibody, the expression pattern of FMNL1 in human tissues and study its subcellular distribution. Our results indicate that FMNL1 expression is not restricted to hematopoietic tissues and that neoexpression of FMNL1 can be seen in epithelial cancer. äCharacterization of Leukocyte Formin FMNL1 Expression in Human Tissues(epmc).pdf DeepDyve Pubget Overpricing