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10.1117/1.JBO.19.9.098004 http://scihub22266oqcxt.onion/10.1117/1.JBO.19.9.098004 C4174533!4174533 !25253195     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25253195 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Biomed+Opt 2014 ; 19 (9 ): 98004 Nephropedia Template TP {{tp|p=25253195 |t=2014. Real-time monitoring of hemodynamic changes in tumor vessels during photoimmunotherapy using optical coherence tomography |pdf=|usr=}}{{25253195 }} gab.com Text Real-time monitoring of hemodynamic changes in tumor vessels during photoimmunotherapy using optical coherence tomography JO: J Biomed Opt http://www.kidney.de/pget.php?&tw=1&pmid=25253195 #FOAvip Photoimmunotherapy (PIT) is a cell-specific cancer therapy based on an armed antibody conjugate that induces rapid and highly selective cancer cell necrosis after exposure to near-infrared (NIR) light. The PIT treatment also induces the superenhanced permeability and retention effect, which allows high concentrations of nanoparticles to accumulate in the tumor bed. In our pilot studies, optical coherence tomography (OCT) reveals dramatic hemodynamic changes during PIT. We developed and applied speckle variance analysis, Doppler flow measurement, bulk motion removal, and automatic region of interest selection to quantify vessel diameter and blood velocity within tumors in vivo. OCT imaging reveals that blood velocity in peripheral tumor vessels quickly drops below the detection limit while the vessel lumen remains open (4 vessels from 3 animals). On the other hand, control tumor vessels (receive NIR illumination but no PIT drug) do not show the sustained blood velocity drop (5 vessels from 3 animals). Ultraslow blood velocity could result in a long drug circulation time in tumor. Increase of the blood pool volume within the central tumor (shown in histology) may be the leading cause of the periphery blood velocity drop and could also increase the drug pool volume in tumor vessels. Twit Text FOAVip Real-time monitoring of hemodynamic changes in tumor vessels during photoimmunotherapy using optical coherence tomography ????J Biomed Opt http://www.kidney.de/pget.php?&tw=1&pmid=25253195 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25253195 #FOAvip English Wikipedia <ref>{{Cite pmid|25253195 }}</ref> Real-time monitoring of hemodynamic changes in tumor vessels during photoimmunotherapy using optical coherence tomography #MMPMID25253195 Liang CP ; Nakajima T ; Watanabe R ; Sato K ; Choyke PL ; Chen Y ; Kobayashi H J Biomed Opt 2014[Sep]; 19 (9 ): 98004 PMID25253195 show ga Photoimmunotherapy (PIT) is a cell-specific cancer therapy based on an armed antibody conjugate that induces rapid and highly selective cancer cell necrosis after exposure to near-infrared (NIR) light. The PIT treatment also induces the superenhanced permeability and retention effect, which allows high concentrations of nanoparticles to accumulate in the tumor bed. In our pilot studies, optical coherence tomography (OCT) reveals dramatic hemodynamic changes during PIT. We developed and applied speckle variance analysis, Doppler flow measurement, bulk motion removal, and automatic region of interest selection to quantify vessel diameter and blood velocity within tumors in vivo. OCT imaging reveals that blood velocity in peripheral tumor vessels quickly drops below the detection limit while the vessel lumen remains open (4 vessels from 3 animals). On the other hand, control tumor vessels (receive NIR illumination but no PIT drug) do not show the sustained blood velocity drop (5 vessels from 3 animals). Ultraslow blood velocity could result in a long drug circulation time in tumor. Increase of the blood pool volume within the central tumor (shown in histology) may be the leading cause of the periphery blood velocity drop and could also increase the drug pool volume in tumor vessels. |Animals [MESH] |Female [MESH] |Hemodynamics/*physiology [MESH] |Immunotherapy [MESH] |Mice [MESH] |Mice, Nude [MESH] |Neoplasms/*blood supply/pathology/physiopathology/*therapy [MESH] |Phantoms, Imaging [MESH] |Phototherapy [MESH] |Tomography, Optical Coherence/*methods [MESH]Real-time monitoring of hemodynamic changes in tumor vessels during (epmc).pdf DeepDyve Pubget Overpricing