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2014 ; 32
(28
): 3126-36
Nephropedia Template TP
gab.com Text
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English Wikipedia
Psychosexual functioning among adult female survivors of childhood cancer: a
report from the childhood cancer survivor study
#MMPMID25113763
Ford JS
; Kawashima T
; Whitton J
; Leisenring W
; Laverdière C
; Stovall M
; Zeltzer L
; Robison LL
; Sklar CA
J Clin Oncol
2014[Oct]; 32
(28
): 3126-36
PMID25113763
show ga
PURPOSE: Childhood cancer survivors may be at risk for impaired psychosexual
functioning as a direct result of their cancer or its treatments, psychosocial
difficulties, and/or diminished quality of life. PATIENTS AND METHODS: Two
thousand one hundred seventy-eight female adult survivors of childhood cancer and
408 female siblings from the Childhood Cancer Survivor Study (CCSS) completed a
self-report questionnaire about their psychosexual functioning and quality of
life. On average, participants were age 29 years (range, 18 to 51 years) at the
time of the survey, had been diagnosed with cancer at a median age of 8.5 years
(range, 0 to 20) and were most commonly diagnosed with leukemia (33.2%) and
Hodgkin lymphoma (15.4%). RESULTS: Multivariable analyses suggested that after
controlling for sociodemographic differences, survivors reported significantly
lower sexual functioning (mean difference [MnD], -0.2; P = .01), lower sexual
interest (MnD, -0.2; P < .01), lower sexual desire (MnD, -0.3; P < .01), lower
sexual arousal (MnD, -0.3; P < .01), lower sexual satisfaction (MnD, -0.2; P =
.01), and lower sexual activity (MnD, -0.1; P = .02) compared with siblings. Risk
factors for poorer psychosexual functioning among survivors included older age at
assessment, ovarian failure at a younger age, treatment with cranial radiation,
and cancer diagnosis during adolescence. CONCLUSION: Decreased sexual functioning
among female survivors of childhood cancers seems to be unrelated to emotional
factors and is likely to be an underaddressed issue. Several risk factors among
survivors have been identified that assist in defining high-risk subgroups who
may benefit from targeted screening and interventions.
|*Surveys and Questionnaires
[MESH]
|Adolescent
[MESH]
|Adult
[MESH]
|Child
[MESH]
|Child, Preschool
[MESH]
|Female
[MESH]
|Hodgkin Disease/diagnosis/psychology
[MESH]
|Humans
[MESH]
|Infant
[MESH]
|Infant, Newborn
[MESH]
|Leukemia/diagnosis/psychology
[MESH]
|Logistic Models
[MESH]
|Middle Aged
[MESH]
|Multivariate Analysis
[MESH]
|Neoplasms/diagnosis/*psychology
[MESH]
|Quality of Life
[MESH]
|Risk Assessment/methods/statistics & numerical data
[MESH]