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10.1016/j.tcm.2014.07.001 http://scihub22266oqcxt.onion/10.1016/j.tcm.2014.07.001 C4171185!4171185 !25112803     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25112803 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Trends+Cardiovasc+Med 2014 ; 24 (7 ): 273-8 Nephropedia Template TP {{tp|p=25112803 |t=2014. Sinus node dysfunction in catecholaminergic polymorphic ventricular tachycardia: risk factor and potential therapeutic target? |pdf=|usr=}}{{25112803 }} gab.com Text Sinus node dysfunction in catecholaminergic polymorphic ventricular tachycardia: risk factor and potential therapeutic target JO: Trends Cardiovasc Med http://www.kidney.de/pget.php?&tw=1&pmid=25112803 #FOAvip Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited heart rhythm disorder characterized by the occurrence of potentially life-threatening polymorphic ventricular tachyarrhythmias in conditions of physical or emotional stress. The underlying cause is a dysregulation in intracellular Ca handling due to mutations in the sarcoplasmic reticulum Ca release unit. Recent experimental work suggests that sinus bradycardia, which is sometimes observed in CPVT patients, may be another primary defect caused by CPVT mutations. Herein, we review the pathophysiology of CPVT and discuss the role of sinus node dysfunction as a modulator of arrhythmia risk and potential therapeutic target. Twit Text FOAVip Sinus node dysfunction in catecholaminergic polymorphic ventricular tachycardia: risk factor and potential therapeutic target ????Trends Cardiovasc Med http://www.kidney.de/pget.php?&tw=1&pmid=25112803 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25112803 #FOAvip English Wikipedia <ref>{{Cite pmid|25112803 }}</ref> Sinus node dysfunction in catecholaminergic polymorphic ventricular tachycardia: risk factor and potential therapeutic target? #MMPMID25112803 Faggioni M ; van der Werf C ; Knollmann BC Trends Cardiovasc Med 2014[Oct]; 24 (7 ): 273-8 PMID25112803 show ga Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited heart rhythm disorder characterized by the occurrence of potentially life-threatening polymorphic ventricular tachyarrhythmias in conditions of physical or emotional stress. The underlying cause is a dysregulation in intracellular Ca handling due to mutations in the sarcoplasmic reticulum Ca release unit. Recent experimental work suggests that sinus bradycardia, which is sometimes observed in CPVT patients, may be another primary defect caused by CPVT mutations. Herein, we review the pathophysiology of CPVT and discuss the role of sinus node dysfunction as a modulator of arrhythmia risk and potential therapeutic target. |*Heart Rate [MESH] |Animals [MESH] |Bradycardia/genetics/metabolism/physiopathology [MESH] |Calcium Signaling [MESH] |Genetic Predisposition to Disease [MESH] |Humans [MESH] |Mutation [MESH] |Phenotype [MESH] |Polymorphic Catecholaminergic Ventricular Tachycardia [MESH] |Risk Factors [MESH] |Ryanodine Receptor Calcium Release Channel/genetics/metabolism [MESH] |Sarcoplasmic Reticulum/metabolism [MESH] |Sick Sinus Syndrome/diagnosis/genetics/metabolism/*physiopathology/therapy [MESH] |Sinoatrial Node/*physiopathology [MESH]Sinus node dysfunction in catecholaminergic polymorphic ventricular ta(epmc).pdf DeepDyve Pubget Overpricing