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10.1038/pr.2014.102 http://scihub22266oqcxt.onion/10.1038/pr.2014.102 C4167942!4167942!25000347     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pediatr+Res 2014 ; 76 (4): 326-33 Nephropedia Template TP {{tp|p=25000347|t=2014. Bifidobacterium longum subsp infantis in experimental necrotizing enterocolitis: alterations in inflammation, innate immune response, and the microbiota |pdf=|usr=}}{{25000347}} gab.com Text Bifidobacterium longum subsp infantis in experimental necrotizing enterocolitis: alterations in inflammation, innate immune response, and the microbiota JO: Pediatr Res http://www.kidney.de/pget.php?&tw=1&pmid=25000347 #FOAvip Background: Probiotics decrease the risk of necrotizing enterocolits (NEC). We sought to determine the impact of Bifidobacterium longum subsp. infantis (B. infantis) in the established rat model of NEC. Methods: Rat pups delivered one day prior to term gestation were assigned to one of three groups: dam-fed (DF), formula-fed (FF), or fed with formula supplemented with 5 × 106 CFU B. infantis per day (FF+Binf). Experimental pups were exposed to hypoxia and cold stress. Ileal tissue was examined for pathology and expression of inflammatory mediators, antimicrobial peptides, and goblet-cell products. Ceca were assessed for bacterial composition by analysis of 16S rRNA sequence. Results: Administration of B. infantis significantly reduced the incidence of NEC, decreased expression of Il6, Cxcl1, Tnfa, Il23, and iNOS, and decreased expression of the antimicrobial peptides Reg3b and Reg3g. There was significant microbial heterogeneity both within groups and between experiments. The cecal microbiota was not significantly different between the FF and FF+Binf groups. Bifidobacteria were not detected in the cecum in significant numbers. Conclusions: In the rat model, the inflammation associated with NEC was attenuated by administration of probiotic B. infantis. Dysbiosis was highly variable precluding determination of the precise role of the microbiota in experimental NEC. Twit Text FOAVip Bifidobacterium longum subsp infantis in experimental necrotizing enterocolitis: alterations in inflammation, innate immune response, and the microbiota ????Pediatr Res http://www.kidney.de/pget.php?&tw=1&pmid=25000347 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25000347 #FOAvip English Wikipedia <ref>{{Cite pmid|25000347}}</ref> Bifidobacterium longum subsp infantis in experimental necrotizing enterocolitis: alterations in inflammation, innate immune response, and the microbiota #MMPMID25000347 Underwood MA; Arriola J; Gerber CW; Kaveti A; Kalanetra KM; Kananurak A; Bevins CL; Mills DA; Dvorak B Pediatr Res 2014[Oct]; 76 (4): 326-33 PMID25000347show ga Background: Probiotics decrease the risk of necrotizing enterocolits (NEC). We sought to determine the impact of Bifidobacterium longum subsp. infantis (B. infantis) in the established rat model of NEC. Methods: Rat pups delivered one day prior to term gestation were assigned to one of three groups: dam-fed (DF), formula-fed (FF), or fed with formula supplemented with 5 × 106 CFU B. infantis per day (FF+Binf). Experimental pups were exposed to hypoxia and cold stress. Ileal tissue was examined for pathology and expression of inflammatory mediators, antimicrobial peptides, and goblet-cell products. Ceca were assessed for bacterial composition by analysis of 16S rRNA sequence. Results: Administration of B. infantis significantly reduced the incidence of NEC, decreased expression of Il6, Cxcl1, Tnfa, Il23, and iNOS, and decreased expression of the antimicrobial peptides Reg3b and Reg3g. There was significant microbial heterogeneity both within groups and between experiments. The cecal microbiota was not significantly different between the FF and FF+Binf groups. Bifidobacteria were not detected in the cecum in significant numbers. Conclusions: In the rat model, the inflammation associated with NEC was attenuated by administration of probiotic B. infantis. Dysbiosis was highly variable precluding determination of the precise role of the microbiota in experimental NEC. äBifidobacterium longum subsp infantis in experimental necrotizing ent(epmc).pdf DeepDyve Pubget Overpricing