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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Pediatric+Infect+Dis+Soc
2014 ; 3 Suppl 1
(Suppl 1
): S24-9
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Mother-to-Child Transmission of Human T-Cell Lymphotropic Viruses-1/2: What We
Know, and What Are the Gaps in Understanding and Preventing This Route of
Infection
#MMPMID25232474
Carneiro-Proietti AB
; Amaranto-Damasio MS
; Leal-Horiguchi CF
; Bastos RH
; Seabra-Freitas G
; Borowiak DR
; Ribeiro MA
; Proietti FA
; Ferreira AS
; Martins ML
J Pediatric Infect Dis Soc
2014[Sep]; 3 Suppl 1
(Suppl 1
): S24-9
PMID25232474
show ga
Although human T-cell lymphotropic viruses (HTLV-1/2) were described over
30?years ago, they are relatively unknown to the public and even to healthcare
personnel. Although HTLV-1 is associated with severe illnesses, these occur in
only approximately 10% of infected individuals, which may explain the lack of
public knowledge about them. However, cohort studies are showing that a myriad of
other disease manifestations may trouble infected individuals and cause higher
expenditures with healthcare. Testing donated blood for HTLV-1/2 started soon
after reliable tests were developed, but unfortunately testing is not available
for women during prenatal care. Vertical transmission can occur before or after
birth of the child. Before birth, it occurs transplacentally or by transfer of
virus during cesarean delivery, but these routes of infection are rare. After
childbirth, viral transmission occurs during breastfeeding and increases with
longer breastfeeding and high maternal proviral load. Unlike the human
immunodeficiency virus types 1 and 2, HTLV is transmitted primarily through
breastfeeding and not transplacentally or during delivery. In this study, we
review what is currently known about HTLV maternal transmission, its prevention,
and the gaps still present in the understanding of this process.