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Aggressive Behavior Problems in Children with Autism Spectrum Disorders:
Prevalence and Correlates in a Large Clinical Sample
#MMPMID25221619
Hill AP
; Zuckerman KE
; Hagen AD
; Kriz DJ
; Duvall SW
; van Santen J
; Nigg J
; Fair D
; Fombonne E
Res Autism Spectr Disord
2014[Sep]; 8
(9
): 1121-1133
PMID25221619
show ga
Aggressive behavior problems (ABP) are frequent yet poorly understood in children
with Autism Spectrum Disorders (ASD) and are likely to co-vary significantly with
comorbid problems. We examined the prevalence and sociodemographic correlates of
ABP in a clinical sample of children with ASD (N = 400; 2-16.9 years). We also
investigated whether children with ABP experience more intensive medical
interventions, greater impairments in behavioral functioning, and more severe
comorbid problems than children with ASD who do not have ABP. One in four
children with ASD had Child Behavior Checklist scores on the Aggressive Behavior
scale in the clinical range (T-scores ? 70). Sociodemographic factors (age,
gender, parent education, race, ethnicity) were unrelated to ABP status. The
presence of ABP was significantly associated with increased use of psychotropic
drugs and melatonin, lower cognitive functioning, lower ASD severity, and greater
comorbid sleep, internalizing, and attention problems. In multivariate models,
sleep, internalizing, and attention problems were most strongly associated with
ABP. These comorbid problems may hold promise as targets for treatment to
decrease aggressive behavior and proactively identify high-risk profiles for
prevention.
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