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10.4161/sgtp.29770 http://scihub22266oqcxt.onion/10.4161/sgtp.29770 C4160341!4160341!24988197     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Small+GTPases 2014 ; 5 (ä): ä Nephropedia Template TP {{tp|p=24988197|t=2014. Rho GTPases as regulators of mitosis and cytokinesis in mammalian cells |pdf=|usr=}}{{24988197}} gab.com Text Rho GTPases as regulators of mitosis and cytokinesis in mammalian cells JO: Small GTPases http://www.kidney.de/pget.php?&tw=1&pmid=24988197 #FOAvip Rho GTPases regulate a diverse range of cellular functions primarily through their ability to modulate microtubule dynamics and the actin-myosin cytoskeleton. Both of these cytoskeletal structures are crucial for a mitotic cell division. Specifically, their assembly and disassembly is tightly regulated in a temporal manner to ensure that each mitotic stage occurs in the correct sequential order and not prematurely until the previous stage is completed. Thus, it is not surprising that the Rho GTPases, RhoA, and Cdc42, have reported roles in several stages of mitosis: cell cortex stiffening during cell rounding, mitotic spindle formation, and bi-orient attachment of the spindle microtubules to the kinetochore and during cytokinesis play multiple roles in establishing the division plane, assembly, and activation of the contractile ring, membrane ingression, and abscission. Here, I review the molecular mechanisms regulating the spatial and temporal activation of RhoA and Cdc42 during mitosis, and how this is critical for mitotic progression and completion. Twit Text FOAVip Rho GTPases as regulators of mitosis and cytokinesis in mammalian cells ????Small GTPases http://www.kidney.de/pget.php?&tw=1&pmid=24988197 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24988197 #FOAvip English Wikipedia <ref>{{Cite pmid|24988197}}</ref> Rho GTPases as regulators of mitosis and cytokinesis in mammalian cells #MMPMID24988197 Chircop M Small GTPases 2014[]; 5 (ä): ä PMID24988197show ga Rho GTPases regulate a diverse range of cellular functions primarily through their ability to modulate microtubule dynamics and the actin-myosin cytoskeleton. Both of these cytoskeletal structures are crucial for a mitotic cell division. Specifically, their assembly and disassembly is tightly regulated in a temporal manner to ensure that each mitotic stage occurs in the correct sequential order and not prematurely until the previous stage is completed. Thus, it is not surprising that the Rho GTPases, RhoA, and Cdc42, have reported roles in several stages of mitosis: cell cortex stiffening during cell rounding, mitotic spindle formation, and bi-orient attachment of the spindle microtubules to the kinetochore and during cytokinesis play multiple roles in establishing the division plane, assembly, and activation of the contractile ring, membrane ingression, and abscission. Here, I review the molecular mechanisms regulating the spatial and temporal activation of RhoA and Cdc42 during mitosis, and how this is critical for mitotic progression and completion. äRho GTPases as regulators of mitosis and cytokinesis in mammalian cell(epmc).pdf DeepDyve Pubget Overpricing