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10.1152/jn.00052.2014 http://scihub22266oqcxt.onion/10.1152/jn.00052.2014 C4157170!4157170 !24966298     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24966298 &cmd=llinks): Failed to open stream: HTTP request failed! 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One month in the life of a neuron: longitudinal single-unit electrophysiology in the monkey visual system |pdf=|usr=}}{{24966298 }} gab.com Text One month in the life of a neuron: longitudinal single-unit electrophysiology in the monkey visual system JO: J Neurophysiol http://www.kidney.de/pget.php?&tw=1&pmid=24966298 #FOAvip Conventional recording methods generally preclude following the activity of the same neurons in awake animals across days. This limits our ability to systematically investigate the principles of neuronal specialization, or to study phenomena that evolve over multiple days such as experience-dependent plasticity. To redress this shortcoming, we developed a drivable, chronically implanted microwire recording preparation that allowed us to follow visual responses in inferotemporal (IT) cortex in awake behaving monkeys across multiple days, and in many cases across months. The microwire bundle and other implanted components were MRI compatible and thus permitted in the same animals both functional imaging and long-term recording from multiple neurons in deep structures within a region the approximate size of one voxel (<1 mm). The distinct patterns of stimulus selectivity observed in IT neurons, together with stable features in spike waveforms and interspike interval distributions, allowed us to track individual neurons across weeks and sometimes months. The long-term consistency of visual responses shown here permits large-scale mappings of neuronal properties using massive image libraries presented over the course of days. We demonstrate this possibility by screening the visual responses of single neurons to a set of 10,000 stimuli. Twit Text FOAVip One month in the life of a neuron: longitudinal single-unit electrophysiology in the monkey visual system ????J Neurophysiol http://www.kidney.de/pget.php?&tw=1&pmid=24966298 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24966298 #FOAvip English Wikipedia <ref>{{Cite pmid|24966298 }}</ref> One month in the life of a neuron: longitudinal single-unit electrophysiology in the monkey visual system #MMPMID24966298 McMahon DB ; Bondar IV ; Afuwape OA ; Ide DC ; Leopold DA J Neurophysiol 2014[Oct]; 112 (7 ): 1748-62 PMID24966298 show ga Conventional recording methods generally preclude following the activity of the same neurons in awake animals across days. This limits our ability to systematically investigate the principles of neuronal specialization, or to study phenomena that evolve over multiple days such as experience-dependent plasticity. To redress this shortcoming, we developed a drivable, chronically implanted microwire recording preparation that allowed us to follow visual responses in inferotemporal (IT) cortex in awake behaving monkeys across multiple days, and in many cases across months. The microwire bundle and other implanted components were MRI compatible and thus permitted in the same animals both functional imaging and long-term recording from multiple neurons in deep structures within a region the approximate size of one voxel (<1 mm). The distinct patterns of stimulus selectivity observed in IT neurons, together with stable features in spike waveforms and interspike interval distributions, allowed us to track individual neurons across weeks and sometimes months. The long-term consistency of visual responses shown here permits large-scale mappings of neuronal properties using massive image libraries presented over the course of days. We demonstrate this possibility by screening the visual responses of single neurons to a set of 10,000 stimuli. |Action Potentials [MESH] |Animals [MESH] |Data Interpretation, Statistical [MESH] |Electrodes, Implanted [MESH] |Female [MESH] |Macaca mulatta [MESH] |Male [MESH] |Neurons/*physiology [MESH] |Photic Stimulation [MESH] |Temporal Lobe/*physiology [MESH]One month in the life of a neuron: longitudinal single-unit electrophy(epmc).pdf DeepDyve Pubget Overpricing