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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 AJNR+Am+J+Neuroradiol
2014 ; 35
(12
): 2209-14
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English Wikipedia
Delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage: proposal of an
evidence-based combined clinical and imaging reference standard
#MMPMID24263697
Sanelli PC
; Kishore S
; Gupta A
; Mangat H
; Rosengart A
; Kamel H
; Segal A
AJNR Am J Neuroradiol
2014[Dec]; 35
(12
): 2209-14
PMID24263697
show ga
Aneurysmal subarachnoid hemorrhage is associated with high morbidity and
mortality, with delayed neurologic deficits from delayed cerebral ischemia
contributing to a large portion of the adverse outcomes in this patient
population. There is currently no consensus reference standard for establishing
the diagnosis of delayed cerebral ischemia either in the research or clinical
settings, ultimately limiting strategies for preventing delayed infarction and
permanent neurologic deficits. There are currently both clinical and
imaging-based criteria for the diagnosis of delayed neurologic deficits and
vasospasm, respectively, however, neither clinical nor angiographic assessment
alone has been shown to identify patients who develop adverse outcomes from
delayed infarction. Thus, the purpose of this work is to propose a 3-tiered
combined imaging and clinical reference standard based on evidence from the
literature to standardize the diagnosis of delayed cerebral ischemia, both to
allow consistency across research studies and to ultimately improve outcomes in
the clinical setting.