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10.1016/j.neuron.2014.08.011

http://scihub22266oqcxt.onion/10.1016/j.neuron.2014.08.011
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C4156912!4156912!25175878
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suck abstract from ncbi


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pmid25175878      Neuron 2014 ; 83 (5): 1002-18
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  • Insights into Human Behavior from Lesions to the Prefrontal Cortex #MMPMID25175878
  • Szczepanski SM; Knight RT
  • Neuron 2014[Sep]; 83 (5): 1002-18 PMID25175878show ga
  • The prefrontal cortex (PFC), a cortical region that was once thought to be functionally insignificant, is now known to play an essential role in the organization and control of goal-directed thought and behavior. Neuroimaging, neurophysiological, and modeling techniques have lead to tremendous advances in our understanding of PFC functions over the last few decades. It should be noted, however, that neurological, neuropathological, and neuropsychological studies have contributed some of the most essential, historical, and often prescient, conclusions regarding the functions of this region. Importantly, examination of patients with brain damage allows one to draw conclusions about whether a brain area is necessary for a particular function. Here, we provide a broad overview of PFC functions based upon behavioral and neural changes resulting from damage to PFC in both human patients and non-human primates.
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