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10.1074/jbc.M114.571869

http://scihub22266oqcxt.onion/10.1074/jbc.M114.571869
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C4155643!4155643!25049234
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suck abstract from ncbi


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pmid25049234      J+Biol+Chem 2014 ; 289 (36): 24736-48
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  • Dual Functions of the Trans-2-Enoyl-CoA Reductase TER in the Sphingosine 1-Phosphate Metabolic Pathway and in Fatty Acid Elongation* #MMPMID25049234
  • Wakashima T; Abe K; Kihara A
  • J Biol Chem 2014[Sep]; 289 (36): 24736-48 PMID25049234show ga
  • Background: The enzyme responsible for the saturation step of the sphingosine 1-phosphate (S1P) metabolic pathway remained unidentified.Results: The trans-2-enoyl-CoA reductase TER, which functions in very long-chain fatty acid (VLCFA) synthesis, catalyzes the saturation step.Conclusion: TER is involved in both VLCFA synthesis and sphingosine degradation within sphingolipids.Significance: Our findings reveal further details of the S1P metabolic pathway.
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