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10.1158/0008-5472.CAN-14-1042 http://scihub22266oqcxt.onion/10.1158/0008-5472.CAN-14-1042 C4155070!4155070!24970480     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cancer+Res 2014 ; 74 (17): 4937-45 Nephropedia Template TP {{tp|p=24970480|t=2014. Live-cell imaging of invasion and intravasation in an artificial microvessel platform |pdf=|usr=}}{{24970480}} gab.com Text Live-cell imaging of invasion and intravasation in an artificial microvessel platform JO: Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=24970480 #FOAvip Methods to visualize metastasis exist, but additional tools to better define the biological and physical processes underlying invasion and intravasation are still needed. One difficulty in studying metastasis stems from the complexity of the interface between the tumor microenvironment and the vascular system. Here we report the development of an investigational platform that positions tumor cells next to an artificial vessel embedded in an extracellular matrix (ECM). On this platform, we used live-cell fluorescence microscopy to analyze the complex interplay between metastatic cancer cells and a functional artificial microvessel which was lined with endothelial cells. The platform recapitulated known interactions, and its use demonstrated the capabilities for a systematic study of novel physical and biological parameters involved in invasion and intravasation. In summary, our work offers an important new tool to advance knowledge about metastasis and candidate anti-metastatic therapies. Twit Text FOAVip Live-cell imaging of invasion and intravasation in an artificial microvessel platform ????Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=24970480 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24970480 #FOAvip English Wikipedia <ref>{{Cite pmid|24970480}}</ref> Live-cell imaging of invasion and intravasation in an artificial microvessel platform #MMPMID24970480 Wong AD; Searson PC Cancer Res 2014[Sep]; 74 (17): 4937-45 PMID24970480show ga Methods to visualize metastasis exist, but additional tools to better define the biological and physical processes underlying invasion and intravasation are still needed. One difficulty in studying metastasis stems from the complexity of the interface between the tumor microenvironment and the vascular system. Here we report the development of an investigational platform that positions tumor cells next to an artificial vessel embedded in an extracellular matrix (ECM). On this platform, we used live-cell fluorescence microscopy to analyze the complex interplay between metastatic cancer cells and a functional artificial microvessel which was lined with endothelial cells. The platform recapitulated known interactions, and its use demonstrated the capabilities for a systematic study of novel physical and biological parameters involved in invasion and intravasation. In summary, our work offers an important new tool to advance knowledge about metastasis and candidate anti-metastatic therapies. äLive-cell imaging of invasion and intravasation in an artificial micro(epmc).pdf DeepDyve Pubget Overpricing