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10.1158/1078-0432.CCR-14-0932

http://scihub22266oqcxt.onion/10.1158/1078-0432.CCR-14-0932
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suck abstract from ncbi


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pmid25059519
      Clin+Cancer+Res 2014 ; 20 (17 ): 4422-4
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  • "Companion diagnostics": has their time come and gone? #MMPMID25059519
  • Hirsch FR ; Bunn PA Jr ; Herbst RS
  • Clin Cancer Res 2014[Sep]; 20 (17 ): 4422-4 PMID25059519 show ga
  • Rapid development of molecularly targeted drugs requires a "companion diagnostic" that could delay drug development and limit availability of active drugs for relevant patients. Were the negative results from MetMab studies in patients with advanced non-small cell lung cancer due to drug failure or failure of the right companion diagnostic?
  • |Antibodies, Monoclonal/*administration & dosage [MESH]
  • |Antineoplastic Combined Chemotherapy Protocols/*administration & dosage [MESH]
  • |Carcinoma, Non-Small-Cell Lung/*drug therapy [MESH]
  • |Erlotinib Hydrochloride [MESH]
  • |Female [MESH]
  • |Humans [MESH]
  • |Male [MESH]
  • |Proto-Oncogene Proteins c-met/*biosynthesis [MESH]


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