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10.7863/ultra.33.9.1597 http://scihub22266oqcxt.onion/10.7863/ultra.33.9.1597 C4145616!4145616 !25154941     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25154941 &cmd=llinks): Failed to open stream: HTTP request failed! 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Noninvasive assessment of liver fibrosis using ultrasound-based shear wave measurement and comparison to magnetic resonance elastography |pdf=|usr=}}{{25154941 }} gab.com Text Noninvasive assessment of liver fibrosis using ultrasound-based shear wave measurement and comparison to magnetic resonance elastography JO: J Ultrasound Med http://www.kidney.de/pget.php?&tw=1&pmid=25154941 #FOAvip OBJECTIVES: Magnetic resonance elastography (MRE) has excellent performance in detecting liver fibrosis and is becoming an alternative to liver biopsy in clinical practice. Ultrasound techniques based on measuring the propagation speed of the shear waves induced by acoustic radiation force also have shown promising results for liver fibrosis staging. The objective of this study was to compare ultrasound-based shear wave measurement to MRE. METHODS: In this study, 50 patients (28 female and 22 male; age range, 19-81 years) undergoing liver MRE examinations were studied with an ultrasound scanner modified with shear wave measurement functionality. For each patient, 27 shear wave speed measurements were obtained at various locations in the liver parenchyma away from major vessels. The median shear wave speed from all measurements was used to calculate a representative shear modulus (?) for each patient. Magnetic resonance elastographic data processing was done by a single analyst blinded to the ultrasound measurement results. RESULTS: Ultrasound and MRE measurements were correlated (r = 0.86; P < .001). Receiver operating characteristic (ROC) analysis was applied to the ultrasound measurement results with the MRE diagnosis as the "ground truth." The area under the ROC curve for separating patients with minimum fibrosis (defined as ?(MRE) ?2.9 kPa) was 0.89 (95% confidence interval, 0.77-0.95), and the area under the ROC curve for separating patients with advanced fibrosis (defined as ?(MRE) ?5.0 kPa) was 0.96 (95% confidence interval, 0.87-0.99). CONCLUSIONS: Results indicate that the ultrasound-based shear wave measurement correlates with MRE and is a promising method for liver fibrosis staging. Twit Text FOAVip Noninvasive assessment of liver fibrosis using ultrasound-based shear wave measurement and comparison to magnetic resonance elastography ????J Ultrasound Med http://www.kidney.de/pget.php?&tw=1&pmid=25154941 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25154941 #FOAvip English Wikipedia <ref>{{Cite pmid|25154941 }}</ref> Noninvasive assessment of liver fibrosis using ultrasound-based shear wave measurement and comparison to magnetic resonance elastography #MMPMID25154941 Zhao H ; Chen J ; Meixner DD ; Xie H ; Shamdasani V ; Zhou S ; Robert JL ; Urban MW ; Sanchez W ; Callstrom MR ; Ehman RL ; Greenleaf JF ; Chen S J Ultrasound Med 2014[Sep]; 33 (9 ): 1597-604 PMID25154941 show ga OBJECTIVES: Magnetic resonance elastography (MRE) has excellent performance in detecting liver fibrosis and is becoming an alternative to liver biopsy in clinical practice. Ultrasound techniques based on measuring the propagation speed of the shear waves induced by acoustic radiation force also have shown promising results for liver fibrosis staging. The objective of this study was to compare ultrasound-based shear wave measurement to MRE. METHODS: In this study, 50 patients (28 female and 22 male; age range, 19-81 years) undergoing liver MRE examinations were studied with an ultrasound scanner modified with shear wave measurement functionality. For each patient, 27 shear wave speed measurements were obtained at various locations in the liver parenchyma away from major vessels. The median shear wave speed from all measurements was used to calculate a representative shear modulus (?) for each patient. Magnetic resonance elastographic data processing was done by a single analyst blinded to the ultrasound measurement results. RESULTS: Ultrasound and MRE measurements were correlated (r = 0.86; P < .001). Receiver operating characteristic (ROC) analysis was applied to the ultrasound measurement results with the MRE diagnosis as the "ground truth." The area under the ROC curve for separating patients with minimum fibrosis (defined as ?(MRE) ?2.9 kPa) was 0.89 (95% confidence interval, 0.77-0.95), and the area under the ROC curve for separating patients with advanced fibrosis (defined as ?(MRE) ?5.0 kPa) was 0.96 (95% confidence interval, 0.87-0.99). CONCLUSIONS: Results indicate that the ultrasound-based shear wave measurement correlates with MRE and is a promising method for liver fibrosis staging. |Adult [MESH] |Aged [MESH] |Aged, 80 and over [MESH] |Elasticity Imaging Techniques/*methods [MESH] |Female [MESH] |Humans [MESH] |Liver Cirrhosis/*diagnostic imaging/*pathology [MESH] |Liver/diagnostic imaging/pathology [MESH] |Magnetic Resonance Imaging/*methods [MESH] |Male [MESH] |Middle Aged [MESH] |ROC Curve [MESH] |Reproducibility of Results [MESH]Noninvasive assessment of liver fibrosis using ultrasound-based shear (epmc).pdf DeepDyve Pubget Overpricing