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Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Spine+(Phila+Pa+1976) 2014 ; 39 (16): 1314-24 Nephropedia Template TP
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Non-Operative Management for Discogenic Back Pain: A Systematic Review #MMPMID24827515
Lu Y; Guzman JZ; Purmessur D; Iatridis JC; Hecht AC; Qureshi SA; Cho SK
Spine (Phila Pa 1976) 2014[Jul]; 39 (16): 1314-24 PMID24827515show ga
Study Design: Systematic review of the literature. Objective: A systematic evaluation of the literature was performed to investigate current non-operative management for the treatment of discogenic low back pain. Summary of Background data: Back pain is a major healthcare concern with up to 39% being discogenic in origin according to one study. Non-operative therapy is likely to be the initial treatment strategy for discogenic low back pain. Methods: Pubmed, Embase and Cochrane Central Register of Controlled Trials (CENTRAL) were searched for clinical studies evaluating non-operative methods of treating discogenic back pain that were published between 2000?2012. Only prospective randomized controlled studies that compared a non-surgical intervention with sham or placebo therapy were included. After removal of duplicate citations, a total of 226 articles were initially identified from the search terms. From these, we identified 11 randomized controlled trials (RCTs) from which data analysis was performed. Results: The 11 RCTs investigated traction therapy, injections and ablative techniques. Results from five RCTs investigating methylene blue injection, steroid injection, ramus communicans ablation, intradiscal electrothermal therapy (IDET) and biacuplasty favored intervention over sham therapy. However, results from the study on methylene blue injections have not been replicated in other RCTs. Evaluation of the selection criteria utilized in the studies on ramus communicans ablation and intradiscal biacuplasty and a stratified analysis of results from the RCTs on IDET casts doubt on whether the conclusions from these RCTs can be applied to the general discogenic pain patient population. Conclusion: There are few high quality studies evaluating non-operative treatments for reducing discogenic low back pain. Although conclusions from several studies favor intervention over sham, it is unclear whether these interventions confer stable long-term benefit. There is some promise in newer modalities such as biacuplasty; however, more inclusive studies need to be performed.
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Spine+(Phila+Pa+1976) 2014 ; 39 (16): 1314-24
