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10.1093/neuonc/nou206.73 http://scihub22266oqcxt.onion/10.1093/neuonc/nou206.73 C4144543/?report=reader!4144543!C4144543     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=C4144543&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Neuro+Oncol 2014 ; 16 (Suppl 3): iii20 Nephropedia Template TP {{tp|p=C4144543|t=2014. THE WARBURG EFFECT AND BEYOND |pdf=|usr=}}{{C4144543}} gab.com Text THE WARBURG EFFECT AND BEYOND JO: Neuro Oncol http://www.kidney.de/pget.php?&tw=1&pmid=C4144543 #FOAvip BACKGROUND: Pyruvate kinase M2 (PKM2) is highly expressed in multiple cancer types and contributes to the Warburg effect. METHODS: We have used various approaches including animal studies, human GBM specimen analyses, and biochemical studies, to understand the cellular functions of PKM2. RESULTS: We have uncovered the mechanisms underlying the upregulation of PKM2, nuclear translocation of PKM2, and metabolic and non-metabolic functions of PKM2 in promoting cancer cell metabolism, proliferation, and cell cycle progression. CONCLUSIONS: We have concluded that the nuclear function of PKM2 is essential for the Warburg effect and brain tumor development. SECONDARY CATEGORY: n/a. Twit Text FOAVip THE WARBURG EFFECT AND BEYOND ????Neuro Oncol http://www.kidney.de/pget.php?&tw=1&pmid=C4144543 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=C4144543 #FOAvip English Wikipedia <ref>{{Cite pmid|C4144543}}</ref> THE WARBURG EFFECT AND BEYOND #MMPMIDC4144543 Lu Z Neuro Oncol 2014[Jul]; 16 (Suppl 3): iii20 PMIDC4144543show ga BACKGROUND: Pyruvate kinase M2 (PKM2) is highly expressed in multiple cancer types and contributes to the Warburg effect. METHODS: We have used various approaches including animal studies, human GBM specimen analyses, and biochemical studies, to understand the cellular functions of PKM2. RESULTS: We have uncovered the mechanisms underlying the upregulation of PKM2, nuclear translocation of PKM2, and metabolic and non-metabolic functions of PKM2 in promoting cancer cell metabolism, proliferation, and cell cycle progression. CONCLUSIONS: We have concluded that the nuclear function of PKM2 is essential for the Warburg effect and brain tumor development. SECONDARY CATEGORY: n/a. äTHE WARBURG EFFECT AND BEYOND (epmc).pdf DeepDyve Pubget Overpricing