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10.1098/rstb.2013.0507 http://scihub22266oqcxt.onion/10.1098/rstb.2013.0507 C4142028!4142028!25135968     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Philos+Trans+R+Soc+Lond+B+Biol+Sci 2014 ; 369 (1652): ä Nephropedia Template TP {{tp|p=25135968|t=2014. The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease |pdf=|usr=}}{{25135968}} gab.com Text The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease JO: Philos Trans R Soc Lond B Biol Sci http://www.kidney.de/pget.php?&tw=1&pmid=25135968 #FOAvip Long non-coding RNAs (lncRNAs) are transcripts with low protein-coding potential that represent a large proportion of the transcriptional output of the cell. Many lncRNAs exhibit features indicative of functionality including tissue-restricted expression, localization to distinct subcellular structures, regulated expression and evolutionary conservation. Some lncRNAs have been shown to associate with chromatin-modifying activities and transcription factors, suggesting that a common mode of action may be to guide protein complexes to target genomic loci. However, the functions (if any) of the vast majority of lncRNA transcripts are currently unknown, and the subject of investigation. Here, we consider the putative role(s) of lncRNAs in neurodevelopment and brain function with an emphasis on the epigenetic regulation of gene expression. Associations of lncRNAs with neurodevelopmental/neuropsychiatric disorders, neurodegeneration and brain cancers are also discussed. Twit Text FOAVip The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease ????Philos Trans R Soc Lond B Biol Sci http://www.kidney.de/pget.php?&tw=1&pmid=25135968 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25135968 #FOAvip English Wikipedia <ref>{{Cite pmid|25135968}}</ref> The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease #MMPMID25135968 Roberts TC; Morris KV; Wood MJA Philos Trans R Soc Lond B Biol Sci 2014[Sep]; 369 (1652): ä PMID25135968show ga Long non-coding RNAs (lncRNAs) are transcripts with low protein-coding potential that represent a large proportion of the transcriptional output of the cell. Many lncRNAs exhibit features indicative of functionality including tissue-restricted expression, localization to distinct subcellular structures, regulated expression and evolutionary conservation. Some lncRNAs have been shown to associate with chromatin-modifying activities and transcription factors, suggesting that a common mode of action may be to guide protein complexes to target genomic loci. However, the functions (if any) of the vast majority of lncRNA transcripts are currently unknown, and the subject of investigation. Here, we consider the putative role(s) of lncRNAs in neurodevelopment and brain function with an emphasis on the epigenetic regulation of gene expression. Associations of lncRNAs with neurodevelopmental/neuropsychiatric disorders, neurodegeneration and brain cancers are also discussed. äThe role of long non-coding RNAs in neurodevelopment, brain function a(epmc).pdf DeepDyve Pubget Overpricing