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10.1074/jbc.M113.544833

http://scihub22266oqcxt.onion/10.1074/jbc.M113.544833
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C4140303!4140303!24825896
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suck abstract from ncbi


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pmid24825896      J+Biol+Chem 2014 ; 289 (26): 17971-9
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  • Semaphorin 3d and Semaphorin 3e Direct Endothelial Motility through Distinct Molecular Signaling Pathways* #MMPMID24825896
  • Aghajanian H; Choi C; Ho VC; Gupta M; Singh MK; Epstein JA
  • J Biol Chem 2014[Jun]; 289 (26): 17971-9 PMID24825896show ga
  • Background: Class 3 semaphorins are guidance molecules for endothelial cells.Results: In multiple endothelial cell assays, semaphorin 3d requires neuropilin 1 or PI3K/Akt but not plexin D1, whereas semaphorin 3e requires plexin D1 but not neuropilin 1 or PI3K/Akt.Conclusion: Semaphorin 3d and 3e utilize different pathways to mediate similar effects in endothelial cells.Significance: Related guidance molecules utilize distinct mechanisms to repel endothelial cells.
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