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10.1074/jbc.M113.541888

http://scihub22266oqcxt.onion/10.1074/jbc.M113.541888
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C4140263!4140263!24838247
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suck abstract from ncbi


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pmid24838247      J+Biol+Chem 2014 ; 289 (26): 18507-13
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  • Intermolecular Transmembrane Domain Interactions Activate Integrin ?IIb?3* #MMPMID24838247
  • Ye F; Kim SJ; Kim C
  • J Biol Chem 2014[Jun]; 289 (26): 18507-13 PMID24838247show ga
  • Background: The relationship between integrin clustering and activation has been controversial.Results: We show that intermolecular transmembrane domain interaction in integrin ?IIb?3 can induce integrin activation.Conclusion: Integrin clustering can enhance integrin activation.Significance: We provide a new mechanism for integrin activation.
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