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10.1002/cphy.c130040 http://scihub22266oqcxt.onion/10.1002/cphy.c130040 C4137912!4137912!24944035     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Compr+Physiol 2014 ; 4 (3): 1201-28 Nephropedia Template TP {{tp|p=24944035|t=2014. Classical Renin-Angiotensin System in Kidney Physiology |pdf=|usr=}}{{24944035}} gab.com Text Classical Renin-Angiotensin System in Kidney Physiology JO: Compr Physiol http://www.kidney.de/pget.php?&tw=1&pmid=24944035 #FOAvip The renin-angiotensin system has powerful effects in control of the blood pressure and sodium homeostasis. These actions are coordinated through integrated actions in the kidney, cardio-vascular system and the central nervous system. Along with its impact on blood pressure, the renin-angiotensin system also influences a range of processes from inflammation and immune responses to longevity. Here, we review the actions of the ?classical? renin-angiotensin system, whereby the substrate protein angiotensinogen is processed in a two-step reaction by renin and angiotensin converting enzyme, resulting in the sequential generation of angiotensin I and angiotensin II, the major biologically active renin-angiotensin system peptide, which exerts its actions via type 1 and type 2 angiotensin receptors. In recent years, several new enzymes, peptides, and receptors related to the renin-angiotensin system have been identified, manifesting a complexity that was previously unappreciated. While the functions of these alternative pathways will be reviewed elsewhere in this journal, our focus here is on the physiological role of components of the ?classical? renin-angiotensin system, with an emphasis on new developments and modern concepts. Twit Text FOAVip Classical Renin-Angiotensin System in Kidney Physiology ????Compr Physiol http://www.kidney.de/pget.php?&tw=1&pmid=24944035 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24944035 #FOAvip English Wikipedia <ref>{{Cite pmid|24944035}}</ref> Classical Renin-Angiotensin System in Kidney Physiology #MMPMID24944035 Sparks MA; Crowley SD; Gurley SB; Mirotsou M; Coffman TM Compr Physiol 2014[Jul]; 4 (3): 1201-28 PMID24944035show ga The renin-angiotensin system has powerful effects in control of the blood pressure and sodium homeostasis. These actions are coordinated through integrated actions in the kidney, cardio-vascular system and the central nervous system. Along with its impact on blood pressure, the renin-angiotensin system also influences a range of processes from inflammation and immune responses to longevity. Here, we review the actions of the ?classical? renin-angiotensin system, whereby the substrate protein angiotensinogen is processed in a two-step reaction by renin and angiotensin converting enzyme, resulting in the sequential generation of angiotensin I and angiotensin II, the major biologically active renin-angiotensin system peptide, which exerts its actions via type 1 and type 2 angiotensin receptors. In recent years, several new enzymes, peptides, and receptors related to the renin-angiotensin system have been identified, manifesting a complexity that was previously unappreciated. While the functions of these alternative pathways will be reviewed elsewhere in this journal, our focus here is on the physiological role of components of the ?classical? renin-angiotensin system, with an emphasis on new developments and modern concepts. äClassical Renin-Angiotensin System in Kidney Physiology (epmc).pdf DeepDyve Pubget Overpricing